1H MRS Reveals Major Changes in Brain Metabolites Induced by Human Pancreatic Cancer Xenografts

Author:Santosh Bharti  Paul Winnard Jr.  Yelena Mironchik  Marie-France Penet  Anirban Maitra  Zaver Bhujwalla  

Author Institution:Johns Hopkins University, School of Medicine  The University of Texas MD Anderson Cancer Center  

Session Type:Traditional Poster  

Session Date:Monday, 18 June 2018  

Session Time:08:15  

Session:Spectroscopy: NMR & Other  

Program Number:1339  

Presentation Time:

Room Number:Exhibition Hall 1336-1345  

Computer Number:

Automatic Myocardium Segmentation using Fully Conventional Network (FCN)

Author:Yan Wang  Peng Cao  Karen Ordovas  Jing Liu  

Author Institution:University of California, San Francisco  

Session Type:Traditional Poster  

Session Date:Thursday, 21 June 2018  

Session Time:08:00  

Session:Machine Learning for Tissue Segmentation & Classification  

Program Number:2734  

Presentation Time:

Room Number:Exhibition Hall 2726-2738  

Computer Number:

Carbon Nanodots as Diamagnetic CEST MRI Contrast Agents for Cell Labeling

Author:Jia Zhang  Minling Gao  Yue Yuan  Yuguo Li  Peter van Zijl  Mingyao Ying  Guanshu Liu  

Author Institution:Johns Hopkins University, School of Medicine  

Session Type:Power Pitch  

Session Date:Monday, 18 June 2018  

Session Time:13:45  

Session:Pitch: Molecular & Metabolic Imaging  

Program Number:0113  

Presentation Time:13:45  

Room Number:Power Pitch Theater A - Exhibition Hall  

Computer Number:

Carbon Nanodots as Diamagnetic CEST MRI Contrast Agents for Cell Labeling

Author:Jia Zhang  Minling Gao  Yue Yuan  Yuguo Li  Peter van Zijl  Mingyao Ying  Guanshu Liu  

Author Institution:Johns Hopkins University, School of Medicine  

Session Type:Electronic Power Pitch Poster  

Session Date:Monday, 18 June 2018  

Session Time:14:45  

Session:Poster: Molecular & Metabolic Imaging  

Program Number:0113  

Presentation Time:13:45  

Room Number:Power Pitch Theater A - Exhibition Hall  

Computer Number:Plasma 12  

Cerebral Blood Volume Mapping using Fourier-Transform based Velocity-Selective Saturation Pulse Trains

Author:Qin Qin  Yaoming Qu  Wenbo Li  Dapeng Liu  Taehoon Shin  Doris Lin  Peter van Zijl  Zhibo Wen  

Author Institution:Ewha Womans University  Johns Hopkins University  Zhujiang Hospital, Southern Medical University  

Session Type:Oral  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Arterial Spin Labeling  

Program Number:0307  

Presentation Time:17:15  

Room Number:W03/04  

Computer Number:

CEST MRI detection of Deoxycytidine Kinase activity using natural deoxycytidine

Author:Zheng Han  Jia Zhang  Yuguo Li  Jing Liu  Peter van Zijl  Guanshu Liu  

Author Institution:Johns Hopkins University  

Session Type:Combined Educational & Scientific Session  

Session Date:Wednesday, 20 June 2018  

Session Time:13:45  

Session:From Molecular Biomarker to Clinical Quantification  

Program Number:0781  

Presentation Time:15:25  

Room Number:S01  

Computer Number:

CEST MRI of 3-O-Methyl-D-Glucose uptake and accumulation in brain tumors

Chemical exchange saturation transfer magnetic resonance imaging of functionalized poly(N, N’-methylene bisacrylamide 4-aminobutanol) gel

Clinical Feasibility Study of an Accelerated 3D Intracranial Magnetic Resonance Angiography Using Compressed-Sensing Algorithm

Author:Zhiyong Lin  Xiaodong Zhang  Ke Wang  Yuan Jiang  Xiaoyu Hu  Yong Huang  Shuai Ma  Yi Liu  Lina Zhu  Zhizheng Zhuo  Jing Liu  Xiaoying Wang  

Author Institution:Peking University First Hospital  Philips Healthcare  

Session Type:Oral  

Session Date:Tuesday, 19 June 2018  

Session Time:08:15  

Session:Application of Neurovascular Methods  

Program Number:0374  

Presentation Time:09:27  

Room Number:N02  

Computer Number:

Comparing the Reproducibility of Commonly Used Magnetic Resonance Spectroscopy Techniques to Quantify Cerebral Glutathione at 3 T

Comparison between 3D white-matter-suppressed MPRAGE and 3D SPACE FLAIR in the 7T MR imaging of tuberous sclerosis complex

Compressed-Sensing Accelerated 3-Dimensional Magnetic Resonance Imaging of Inner Ear: A Feasibility Study of Volunteer

Author:Yuan Jiang  Lina Zhu  Jing Liu  Xiaodong Zhang  Shuai Ma  Yi Liu  Zhiyong Lin  Ke Wang  Zhizheng Zhuo  Xiaoying Wang  

Author Institution:Peking University First Hospital  Philips Healthcare  

Session Type:Traditional Poster  

Session Date:Tuesday, 19 June 2018  

Session Time:16:15  

Session:Head & Neck  

Program Number:1961  

Presentation Time:

Room Number:Exhibition Hall 1961-1971  

Computer Number:

CORTICAL BONE VESSEL IDENTIFICATION ON CONTRAST-ENHANCED MR IMAGES

Author:Po-hung Wu  Jing Liu  Julio Carballido-Gamio  Misung Han  Roland Krug  Galateia Kazakia  

Author Institution:University of California - San Francisco  University of Colorado Denver - Anschutz Medical Campus  

Session Type:Oral  

Session Date:Thursday, 21 June 2018  

Session Time:15:30  

Session:Little Bones  

Program Number:1250  

Presentation Time:17:18  

Room Number:S05  

Computer Number:

COX-2 Alters the Metabolic Secretome in Triple Negative Human Breast Cancer Xenografts

Author:Santosh Bharti  Paul Winnard Jr.  Yelena Mironchik  Louis Dore-Savard  Balaji Kirshnamachary  Zaver Bhujwalla  

Author Institution:Johns Hopkins University, School of Medicine  McGill University Health Centre and RI-MUHC  

Session Type:Oral  

Session Date:Tuesday, 19 June 2018  

Session Time:16:15  

Session:Tumour Microenvironment  

Program Number:0635  

Presentation Time:17:39  

Room Number:W05/06  

Computer Number:

Cross-vendor standardization of a 3 T MRS protocol with semi-LASER

Author:Adam Berrington  Dinesh Deelchand  James Joers  Michal Považan  Michael Schär  Joseph Gillen  Peter Barker  Gülin Öz  

Author Institution:Johns Hopkins University School of Medicine  University of Minnesota  

Session Type:Traditional Poster  

Session Date:Monday, 18 June 2018  

Session Time:08:15  

Session:MRS/MRSI Aquisition  

Program Number:1276  

Presentation Time:

Room Number:Exhibition Hall 1271-1304  

Computer Number:

Dedicated 3-Channel Surface Coil for Interventional Magnetic Resonance Imaging at 3T - First Evaluation

Author:Lena Sonnow  Wesley Gilson  Arne Hengerer  Clifford Weiss  Himanshu Bhat  Frank Wacker  Jan Fritz  

Author Institution:Hannover Medical School  Siemens Healthcare USA  The Johns Hopkins University School of Medicine  

Session Type:Electronic Poster  

Session Date:Tuesday, 19 June 2018  

Session Time:14:45  

Session:MR-Guided Interventions (Not Thermo nor HIFU)  

Program Number:4172  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 22  

Detection of the accumulation of mannitol in rat brains using CEST MRI

Author:Jing Liu  Chengyan Chu  Lin Chen  Jia Zhang  Rohit Srivatava  Piotr Walczak  Jiadi Xu  Peter van Zijl  Miroslaw Janowski  Guanshu Liu  

Author Institution:The Johns Hopkins University School of Medicine  

Session Type:Electronic Poster  

Session Date:Wednesday, 20 June 2018  

Session Time:17:15  

Session:Advancements in CEST Methodology & Applications  

Program Number:5116  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 36  

Editing everything with HERCULES: Hadamard-encoded editing of seven low-concentration metabolites

Author:Georg Oeltzschner  Daniel Rimbault  Mark Mikkelsen  Muhammad Saleh  Nicolaas Puts  Richard Edden  

Author Institution:The Johns Hopkins University School of Medicine  University of Cape Town  

Session Type:Electronic Poster  

Session Date:Tuesday, 19 June 2018  

Session Time:09:15  

Session:J-Difference-Edited MRS/MRSI  

Program Number:3962  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 52  

The Effect of Altered Glucose Utilization on Dynamic GlucoCEST in a Preclinical Model of Glioblastoma

Author:Xiang Xu  Jing Liu  Jiadi Xu  Linda Knutsson  Huanling Liu  Yuguo Li  Bachchu Lal  John Laterra  Peter van Zijl  Kannie Chan  

Author Institution:Johns Hopkins University  Johns Hopkins University School of Medicine  

Session Type:Oral  

Session Date:Thursday, 21 June 2018  

Session Time:13:15  

Session:Predictive & Prognostic Cancer Imaging  

Program Number:1162  

Presentation Time:14:15  

Room Number:S04  

Computer Number:

Evaluation of different postprocessing-based B0 inhomogeneity correction methods for application in 7T FID-MRSI

Evaluation the Feasibility of Integrating Computer-aided Diagnosis as a Second Reader into Prostate Multiparametric MRI Diagnostic Process

Author:Lina Zhu  Ge Gao  Xiaoying Wang  Jing Liu  Rui Wang  Kai Zhao  Yuan Jiang  

Author Institution:Peking University First Hospital  

Session Type:Electronic Poster  

Session Date:Tuesday, 19 June 2018  

Session Time:16:15  

Session:Prostate 1: Clinical  

Program Number:4369  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 100  

Exploring Glutamate and Glutamine Metabolism Across Breast Cancer Subtypes using High-resolution Proton MRS Combined with Molecular Approaches

Author:Caitlin Tressler  Vinay Ayyappan  Kristine Glunde  

Author Institution:Johns Hopkins University School of Medicine  

Session Type:Electronic Poster  

Session Date:Tuesday, 19 June 2018  

Session Time:09:15  

Session:Spectroscopy: NMR & Other  

Program Number:4025  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 115  

Fluorine labeling and imaging of biomaterial scaffolds for regenerative medicine

Author:Marcin Piejko  Piotr Walczak  Xiaowei Li  Jeff Bulte  Miroslaw Janowski  

Author Institution:Johns Hopkins University  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:17:15  

Session:MR/PET & Molecular Imaging  

Program Number:3696  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 24  

Fully-Automated One-Button-Push 10-min 3D CAIPIRINHA SPACE TSE MRI of the Knee: A Multi-Center Multi-Reader Multi-Field-Strength Validation Study

Author:Filippo Del Grande  Marco Delcogliano  Riccardo Guglielmi  Esther Raithel  Derek Papp  Steven Stern  Christian Candrian  Jan Fritz  

Author Institution:Bond Business School  Ospedale Regionale di Lugano  Siemens Healthcare GmbH  The Johns Hopkins University School of Medicine  

Session Type:Oral  

Session Date:Thursday, 21 June 2018  

Session Time:08:00  

Session:MSK: Harder, Better, Faster, Stronger  

Program Number:1040  

Presentation Time:08:36  

Room Number:S02  

Computer Number:

GABA levels in children with Autism and typically developing children differentially relate to social gesture performance

Author:Nicolaas Puts  Ashley Harris  Georg Oeltzschner  Mark Mikkelsen  Stewart Mostofsky  Richard Edden  

Author Institution:The Johns Hopkins University School of Medicine  University of Calgary  

Session Type:Oral  

Session Date:Wednesday, 20 June 2018  

Session Time:13:45  

Session:Pediatric Neuropathology & Neurodevelopmental Disorders  

Program Number:0852  

Presentation Time:15:33  

Room Number:W03/04  

Computer Number:

Gene Expression Profiling to Understand the 1H MRS Characterization of the VEGF Metabolic Secretome from a Triple Negative Human Breast Cancer Xenograft

Author:Santosh Bharti  Balaji Kirshnamachary  Louis Dore-Savard  Brett Stark  Aleksander Popel  Zaver Bhujwalla  

Author Institution:Johns Hopkins University, School of Medicine  McGill University Health Centre and RI-MUHC  

Session Type:Traditional Poster  

Session Date:Monday, 18 June 2018  

Session Time:08:15  

Session:Spectroscopy: NMR & Other  

Program Number:1338  

Presentation Time:

Room Number:Exhibition Hall 1336-1345  

Computer Number:

Glycerophosphocholine increase is a reliable surrogate marker of chemotherapy response for various cancer drug treatments in triple-negative breast cancer cells

Author:Menglin Cheng  Vinay Ayyappan  Ruoqing Cai  Caitlin Tressler  Kristine Glunde  

Author Institution:The Johns Hopkins University School of Medicine  

Session Type:Oral  

Session Date:Wednesday, 20 June 2018  

Session Time:13:45  

Session:Imaging Response to Therapy  

Program Number:0803  

Presentation Time:13:45  

Room Number:S03  

Computer Number:

High-resolution total Creatine mapping of the mouse brain at 11.7T using CEST

Author:Lin Chen  Zhiliang Wei  Xiang Xu  Yuguo Li  Shuhui Cai  Guanshu Liu  Hanzhang Lu  Peter Barker  Robert Weiss  Peter van Zijl  Jiadi Xu  

Author Institution:Johns Hopkins University  Xiamen University  

Session Type:Traditional Poster  

Session Date:Wednesday, 20 June 2018  

Session Time:08:15  

Session:CEST: Novel Methods & Applications  

Program Number:2248  

Presentation Time:

Room Number:Exhibition Hall 2222-2249  

Computer Number:

How does inclusion of different macromolecular baseline models affect reproducibility of 1H-FID MRSI in the brain at 7T?

Imaging Blood Brain Barrier Disruption in Multiple Sclerosis using GlucoCEST MRI

Author:Xiang Xu  Pavan Bhargava  Linda Knutsson  Martin Pomper  Peter Calabresi  Peter van Zijl  

Author Institution:Johns Hopkins University  

Session Type:Electronic Poster  

Session Date:Wednesday, 20 June 2018  

Session Time:14:45  

Session:Blood Brain Barrier & CSF Flow  

Program Number:4923  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 57  

Imaging Microscopic Background Gradient Variations in the Mouse Brain

Author:Choong Lee  Piotr Walczak  Lindsay Hill  Youssef Wadghiri  Jiangyang Zhang  

Author Institution:Johns Hopkins University School of Medicine  New York University School of Medicine  

Session Type:Oral  

Session Date:Wednesday, 20 June 2018  

Session Time:16:15  

Session:Microstructure: Moving Through Time  

Program Number:0890  

Presentation Time:17:39  

Room Number:N01  

Computer Number:

The Immune Checkpoint PD-L1 and Choline Kinase-a are inversely related in triple negative human breast cancer cells

Author:Jesús Pacheco-Torres  Marie-France Penet  Yelena Mironchik  Balaji Krishnamachary  Zaver Bhujwalla  

Author Institution:The Johns Hopkins University School of Medicine  

Session Type:Traditional Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Cancer Imaging  

Program Number:1533  

Presentation Time:

Room Number:Exhibition Hall 1509-1553  

Computer Number:

Impaired oxygen metabolism in the brain during visual stimulation in premanifest Huntington's Disease patients detected by 3D-TRIP MRI at 7T

Impaired oxygen metabolism in the brain during visual stimulation in premanifest Huntington's Disease patients detected by 3D-TRIP MRI at 7T

In Vivo iCEST MRI Detection of Zinc Depletion in an Orthotopic Prostate Cancer Mouse Model

Author:Yue Yuan  Chengyan Chu  Zhiliang Wei  Xiaolei Song  Jeff Bulte  

Author Institution:The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Molecular Imaging  

Program Number:3579  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 27  

In vivo Kinetic CEST MRI of sodium salicylate(NaSA): Comparison of MTRasym and Subtraction of saturation-weighted images

Author:Yanrong Chen  Chengwang Jin  Yan Luo  Chongxue Bie  Yingcheng Zhao  Xiaowei He  Xiaolei Song  

Author Institution:Huazhong University of Science and Technology  Northwest University  The Johns Hopkins University  

Session Type:Electronic Poster  

Session Date:Wednesday, 20 June 2018  

Session Time:17:15  

Session:Advancements in CEST Methodology & Applications  

Program Number:5121  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 41  

Increased spatial resolution of MR Spectroscopic Imaging improves the detectability of metabolic changes in Multiple Sclerosis lesions

Author:Eva Heckova  Gilbert Hangel  Bernhard Strasser  Michal Považan  Assunta Dal-Bianco  Paulus Rommer  Elisabeth Springer  Stephan Gruber  Siegfried Trattnig  Wolfgang Bogner  

Author Institution:Harvard Medical School  Medical University of Vienna  The Johns Hopkins University School of Medicine  

Session Type:Oral  

Session Date:Thursday, 21 June 2018  

Session Time:13:15  

Session:MRS Applications  

Program Number:1154  

Presentation Time:14:39  

Room Number:S03  

Computer Number:

Intraarterial chemotherapy of glioblastoma following osmotic blood-brain barrier opening under real-time MRI guidance

Intracellular Assembly of Olsalazine Nanoparticles for CEST MR Imaging and Cancer Therapy

Investigation of Anterior Cingulate Cortex ?-Aminobutyric Acid and Glutamate-Glutamine Levels in Patients with Obsessive-Compulsive Disorder by Proton Magnetic Resonance Spectroscopy

Author:Yan Li  Naying He  Hongmin Xv  Zhijia Jin  ChenCheng Zhang  Weibo Chen  Yansong Zhao  Richard A. E. Edden  Fuhua Yan  

Author Institution:Philips Healthcare  Ruijin Hospital Shanghai Jiaotong University School of Medicine  The Johns Hopkins University School of Medicine  

Session Type:Oral  

Session Date:Thursday, 21 June 2018  

Session Time:13:15  

Session:MRS Applications  

Program Number:1153  

Presentation Time:14:27  

Room Number:S03  

Computer Number:

Joint estimation applied to attenuation correction for quiescent period respiratory gated PET data in PET/MR

Author:Sangtae Ahn  Jaewon Yang  Jing Liu  Youngho Seo  Thomas Hope  Peder Larson  Florian Wiesinger  

Author Institution:GE Global Research  GE Healthcare  University of California, San Francisco  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:17:15  

Session:MR/PET & Molecular Imaging  

Program Number:3686  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 14  

­Lentiviral shRNA-mediated targeting of GDPD5 and GDPD6 in Orthotopic Human Breast Cancer Xenograft Models: A Metabolomics Study

Author:Kanchan Sonkar  Marina Stukova  Caitlin Tressler  Balaji Krishnamachary  Zaver Bhujwalla  Kristine Glunde  

Author Institution:Johns Hopkins University School of Medicine  San Juan Bautista School of Medicine  

Session Type:Traditional Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Cancer Imaging  

Program Number:1530  

Presentation Time:

Room Number:Exhibition Hall 1509-1553  

Computer Number:

Liver metabolomic investigation of lentiviral targeting of GDPD5 and GDPD6 for breast cancer treatment in a preclinical model

Author:Kanchan Sonkar  Marina Stukova  Caitlin Tressler  Balaji Krishnamachary  Zaver Bhujwalla  Kristine Glunde  

Author Institution:Johns Hopkins University School of Medicine  San Juan Bautista School of Medicine  

Session Type:Traditional Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Cancer Imaging  

Program Number:1547  

Presentation Time:

Room Number:Exhibition Hall 1509-1553  

Computer Number:

Mean Transit Time as a Marker of Vascular Change in Asymptomatic White Matter Disease

Author:Blake Dewey  Xiang Xu  Linda Knutsson  Amod Jog  Jerry Prince  Peter Barker  Peter van Zijl  Paul Nyquist  

Author Institution:Harvard Medical School  Johns Hopkins University  Lund University  

Session Type:Traditional Poster  

Session Date:Tuesday, 19 June 2018  

Session Time:16:15  

Session:Neurovascular Imaging Methods  

Program Number:1896  

Presentation Time:

Room Number:Exhibition Hall 1868-1902  

Computer Number:

Metabolic Consequences in the Heart and Skeletal Muscle of Human Pancreatic Cancer Xenograft Growth

Author:Santosh Bharti  Paul Winnard Jr.  Yelena Mironchik  Marie-France Penet  Zaver Bhujwalla  

Author Institution:Johns Hopkins University, School of Medicine  

Session Type:Traditional Poster  

Session Date:Monday, 18 June 2018  

Session Time:08:15  

Session:MRS Animal Studies  

Program Number:1365  

Presentation Time:

Room Number:Exhibition Hall 1361-1368  

Computer Number:

Metal-Free Contrast Agents

Author:Peter van Zijl  

Author Institution:

Session Type:Member-Initiated Symposium  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Safety & Efficacy of Contrast Agents: State of the Art, Future Directions, & Alternative Approaches  

Program Number:

Presentation Time:17:40  

Room Number:N01  

Computer Number:

    Monitoring LPS-induced gray matter inflammation through endogenous contrasts: MT, CEST and NOE

    MPI Cell Tracking: How Does It Compare to MRI?

    Author:Miroslaw Janowski  

    Author Institution:Johns Hopkins University  

    Session Type:Member-Initiated Symposium  

    Session Date:Wednesday, 20 June 2018  

    Session Time:08:15  

    Session:Magnetic Particle Imaging & Its Synergies with MRI Technology & Applications  

    Program Number:

    Presentation Time:09:00  

    Room Number:S01  

    Computer Number: