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SMRT Poster Presentations
Weekend and Oral

Digital Poster (no CME credit)

SMRT Ed Session

SMRT Poster Presentations

SMRT Poster Awards Session

SMRT Posters
 SMRT

S11
Non-gated and non-enhanced MR Angiography of the Hand using enhanced acceleration selective arterial spin labeling (eAccASL)
Misaki Saito1, Shuhei Shibukawa1, Natsuo Konta1, Takuya Hara2, Takakiyo Nomura2, Makoto Obara3, Isao Muro1, and Tetsu Niwa2

1radiological technology, Tokai university hospital, Isehara, Japan, 2Tokai University School of Medicine, Isehara, Japan, 3Philips Japan, Tokyo, Japan

This study was conducted to optimize the enhanced Acceleration-Selective Arterial Spin Labeling (eAccASL) for non-gated hand MRA. The MRA images obtained using four acceleration encoding (AENC) were assessed by visual evaluation for arterial depiction and venous contamination. The blood flow velocity obtained by phase-contrast cine was compared with the visual evaluation. It was found that the smaller the AENC (i.e. stronger motion sensitize gradients), the higher venous contamination and higher arterial visualization. The tendency of high visual evaluation was found in subjects with fast blood flow. The AENC of 0.5 or 1.0 was optimized for non-gated MRA of the hand.

S80 A finding of Female Adnexal Tumour of probable Wolffian Origin (FATWO) on magnetic resonance imaging and histology - a rare neoplasm: Case report
Petronella Samuels1, Paul Scholtz2, Judith Whittaker3, and Sally Candy4

1Cape Universities Body Imaging Centre, University of Cape Town, Cape Town, South Africa, 2Department of Radiology, Morton & Partners Radiology, Cape Town, South Africa, 3Anatomical Pathology, Lancet Laboratories, Cape Town, South Africa, 4Division of Diagnostic Radiology, Groote Schuur Hospital and University of Cape Town, Cape Town, South Africa

We present the MRI and histological findings in a case of Female Adnexal Tumour of Wolffian Origin (FATWO) / WAT (Wolffian Adnexal Tumour), a rare adnexal neoplasm. This mass, located in the right broad ligament demonstrated diffusely low signal intensity on both T2WI and T1WI, peripheral restriction on DWI, peripheral enhancement and central hypo-enhancement post Gadolinium. An awareness of this condition and its MRI findings will ensure that appropriate immunohistochemical staining is performed. The presence of restriction may be helpful in predicting tumour behaviour, surgical approach and postoperative management.

 


S4
Investigation of new assessment method for the liver magnetic resonance imaging
Yasuo Takatsu1,2, Masafumi Nakamura3, Satoshi Kobayashi4, and Tosiaki Miyati4

1Department of Radiological Technology, Faculty of Health and Welfare, Tokushima Bunri University, Sanuki-city, Japan, 2Department of System Control Engineering, Graduate School of Engineering, Tokushima Bunri University, Sanuki-city, Japan, 3Department of Radiology, Otsu City Hospital, Otsu, Japan, 4Division of Health Sciences, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan

The hepatobiliary phase image using Gd–EOB–DTPA in the liver MRI is assessed by the quantitative liver–spleen contrast ratio (Q-LSC) , the cutoff value at which tumors can be easily determined is 1.5. However, Q-LSC is found unsuitable for cases of splenectomy and when there is splenic deposition of Gamna–Gandy bodies. Therefore, the quantitative liver-portal vein contrast ratio (Q-LPC) is useful instead of Q-LSC. The cutoff value of Q-LPC was at 1.462, the sensitivity and the specificity were higher than Q-LSC at the cutoff value. Q-LPC cutoff value can be used for hepatobiliary phase MR image evaluation.

S12
The Effect of Enlarging Shim Volume on B0 homogeneity of MRS Voxel on 7T
Huijun Liao1, Eduardo Jorge Uribe Coello1, Wufan Zhao1, Han Sam Jiang1, and Alexander Lin1

1Center for Clinical Spectroscopy, Brigham and Women's Hospital, Boston, MA, United States

B0 homogeneity is important for clinical spectroscopy but is highly region dependent and time consuming.  Enlarging shim volume could be a quick and easy way to improve B0 homogeneity in the clinical practice of spectroscopy and the goal of this study is test if this method is beneficial.  We used different methods to measure the potential improvement in B0 homogeneity in different brain regions.  While our results showed that increasing shim volumes did not improve spectral linewidths or data quality, we demonstrate a robust method of measuring B0 homogeneity in clinical spectroscopy.

S30
Depicting capsular injury and disc tears of the sternoclavicular joint with the use of direct MRI arthrography
Helen Harvey1

1MRI, Cambridge University Hospitals, Cambridge, United Kingdom

Advances in technology in MRI have allowed for the improved spatial resolution of small joints like the sternoclavicular joint (SCJ). We have shown that through the use of arthrography and MRI we can provide better visualisation of SCJ anatomy, disc tears and other pathologies. Helping to increase knowledge and greatly improve treatment and surgical planning options for the patient.

This presentation aims to understand the techniques for MRI arthrography of the SCJ, review anatomy demonstrated on SCJ arthrography and demonstrate common pathologies of the SCJ.


S74
Optimization of Radial K-space Sampling Techniques for a Comprehensive Motion-free Cervical Spine MRI Protocol
Brian Johnson1, Jonathan Chia1, Dave Hitt1, Rob Lay1, Tom Lowe1, Michael Pawlak1, John Penatzer1, James Snicer1, Marcie Stopchinski1, Gregory Thomas1, Kristen Williams1, and Paul Worthington1

1Philips Healthcare, Gainesville, FL, United States

Consistent high-quality magnetic resonance imaging (MRI) of the cervical spine still remains challenging because of the inherent small anatomical structures and degradation of image quality due to motion artifacts1.  Motion artifacts can arise from several sources including swallowing, respiration, cerebrospinal fluid (CSF) pulsation, blood flow, and bulk patient movement.  MRI of the cervical spine is one the highest performed exams globally.  Here we present a complete cervical spine MRI protocol utilizing 2D and 3D radial k-space sampling techniques which are inherently motion insensitive to increase image quality.  

S39
A Single Breath-Hold Acquisition of Three-Dimensional T1 Mapping Using Look Locker sequence for Assessing Crohn Disease: A Phantom Study
Daisuke Morimoto-Ishikawa1,2, Tomoko Hyodo3, Shigeyoshi Saito2, Yu Ueda4, Masato Ohmi2, and Kazunari Ishii3

1Radiology Center, Kindai University Hospital, Osaka-Sayama, Japan, 2Department of Medical Physics and Engineering, Osaka University Graduate School of Medicine, Suita, Japan, 3Department of Radiology, Kindai University, Osaka-Sayama, Japan, 4Philips Japan, Tokyo, Japan

We investigated the single breath-hold three-dimensional (3D) Look-Locker (LL) sequence in nine different concentrations phantoms, which can be used to evaluate Crohn's disease (CD). Percentage errors between T1 relaxation time obtained by varying inversion recovery pulse interval and recovery period in the LL sequence and T1 relaxation time obtained by the Inversion Recovery sequence were calculated. With the combination of inversion recovery pulse interval of 7000ms and recovery period of 4000ms, the LL sequence can calculate T1 relaxation time within 10% percentage errors in the fastest imaging time of 21 seconds.

S34
Effects of image quality deterioration and data shortage on automatic white matter bundle segmentation by diffusion magnetic resonance imaging
Yuichi Suzuki1, Tsuyoshi Ueyama1, Takahiro Iwasaki1, Jiro Sato1, Hideyuki Iwanaga1, and Osamu Abe1

1Department of Radiology, THe University of Tokyo Hospital, Tokyo, Japan

We investigated the effect of image quality deterioration and data shortage of DWI on automatic white matter bundle segmentation. We set the gold standard (GS) data without SMS and MPG = 64 axes. Two kinds of comparisons were made in comparison with GS data. The one was with/without the SMS, and the other eliminated some acquired data from GS. We analyze the data only from the first 8, 16, 32 and 48 axes of MPG in the GS. There was almost no difference between SMS of 2 and 3. For MPG, 16 axes provided results comparable to the GS.

S90
Deep Inspiration Breath-Hold Radiotherapy does not induce MRI detectable LV functional and structural changes in patients with left-sided breast cancer – A six months follow-up
Xin Dong1,2, Arnold Ng3,4, Sharon Watson5, Harish Sharma5, Graham Galloway1,2,6, and Margot Lehman5

1Queensland University of Technology, Brisbane, Australia, 2Translational Research Institute, Woolloongabba, Australia, 3Cardiology, Princess Alexandra Hospital, Brisbane, Australia, 4University of New South Wales, Sydney, Australia, 5Radiation Oncology, Princess Alexandra Hospital, Brisbane, Australia, 6The University of Queensland, St Lucia, Australia

The usefulness of T1 and ECV mappings in the context of radiation cardiotoxicity has yet to be studied. In the current study, we conducted a longitudinal CMR study on 30 females with left-sided breast cancer before and after Deep Inspiration Breast Hold (DIBH) radiotherapy (RT). The results showed patients who were treated with DIBH RT had no CMR detectable functional or structural myocardial changes 6 months following RT treatment. This has important implications on the long-term cardiac health of the growing number of women who are surviving or living with breast cancer.

S44
Optimization of Variable TI 4D ultrashort TE MR Angiography: A Numerical Simulation and Phantom Study
Toshiya Akatsu1, Haruyuki Fukuchi2,3,4, Kei Fukuzawa4, Nao Takano1, Yutaka Ikenouchi3, Michimasa Suzuki3, Kohji Kamagata3, Akihiko Wada3, Osamu Abe2, and Shigeki Aoki3

1Department of Radiology, Juntendo University Hospital, Tokyo, Japan, 2Department of Radiology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan, 3Department of Radiology, Juntendo University Graduate School of Medicine, Tokyo, Japan, 4Department of Radiology, Toranomon Hospital, Tokyo, Japan

We implemented the new Variable TI method to multi-phase ASL 4D UTE-MRA in order to improve the visibility of hemodynamic flow. We performed a numerical simulation and a phantom study to find the optimized condition. It was found that a 50 % reduction of TI steps increases 50 % of signal from the flow volume without impairment of structural information.

S19 Optimizing dark blood late gadolinium enhancement in cardiac magnetic resonance imaging.
Hannah Bergman1, Alaine Berry1, and Ben Statton1

1MRC, Imperial College, London, United Kingdom

The dark blood late gadolinium enhancement technique has shown improved delineation of sub-endocardial infarcts by nulling both the blood pool and the normal myocardium. Optimal image quality and consistency depends on a number of factors, including gadolinium dose and the delay time before imaging. In this study we sought to determine whether gadolinium dose and delay time before imaging, affected the nulling of the blood pool and myocardium.

S7
Optimized 3D ultrashort TE protocol for lung imaging
CHIKARA NODA1, Chia Ying Liu2, Jason Ortman1, Bharath Venkatesh Ambale3, Webster Stayman4, Yoshimori Kassai5, and Joao A.C. Lima1

1Cardiology, Johns Hopkins University, Baltimore, MD, United States, 2Canon Medical Research, Cleveland, OH, United States, 3Radiology, Johns Hopkins University, Baltimore, MD, United States, 4Biomedical Engineering, Johns Hopkins University, Baltimore, MD, United States, 5Canon Medical Systems Corporation, Otawara, Japan

3D radial Ultrashort echo time sequence is a promising technique for lung imaging but the protocol has not been optimized. We examined the parameters including number of trajectories and flip angles using a lung phantom. In-vivo images were obtained and evaluated based on the parameters optimized in the phantom study. UTE acquisition in axial rather than coronal direction produced better quality of images. Breath holding acquisition may be an option in case patients cannot tolerate long scan time.

S60
Osteoporotic vertebral fracture analysis with intravoxel incoherent motion: a preliminary study
Hiroyuki Takashima1,2, Rui Imamura1, Tsuneo Takebayashi3, Yasuhisa Abe3, Izaya Ogon2, Hiroshi Oguma3, Yoshihiro Akatsuka1, and Toshihiko Yamashita2

1Division of Radiology and Nuclear Medicine, Sapporo Medical University Hospital, Sapporo, Japan, 2Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, Sapporo, Japan, 3Department of Orthopaedic Surgery, Sapporo Maruyama Orthopedic Hospital, Sapporo, Japan

The parameters of vertebral fracture (VF) and without fracture using intravoxel incoherent motion (IVIM) were analyzed. In addition, the usefulness of using IVIM for VF was investigated. The subjects of this study were 52 patients with VF in the acute phase. As a result, the ADC, D, and f of VF were significantly higher than without fracture. Meanwhile, the D* of VF were significantly lower than without fracture. In the future, new findings may be obtained by analyzing the IVIM parameters and VF prognosis.


SMRT Poster Presentations: Clinical

SMRT Posters
 SMRT

S4
Investigation of new assessment method for the liver magnetic resonance imaging
Yasuo Takatsu1,2, Masafumi Nakamura3, Satoshi Kobayashi4, and Tosiaki Miyati4

1Department of Radiological Technology, Faculty of Health and Welfare, Tokushima Bunri University, Sanuki-city, Japan, 2Department of System Control Engineering, Graduate School of Engineering, Tokushima Bunri University, Sanuki-city, Japan, 3Department of Radiology, Otsu City Hospital, Otsu, Japan, 4Division of Health Sciences, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan

The hepatobiliary phase image using Gd–EOB–DTPA in the liver MRI is assessed by the quantitative liver–spleen contrast ratio (Q-LSC) , the cutoff value at which tumors can be easily determined is 1.5. However, Q-LSC is found unsuitable for cases of splenectomy and when there is splenic deposition of Gamna–Gandy bodies. Therefore, the quantitative liver-portal vein contrast ratio (Q-LPC) is useful instead of Q-LSC. The cutoff value of Q-LPC was at 1.462, the sensitivity and the specificity were higher than Q-LSC at the cutoff value. Q-LPC cutoff value can be used for hepatobiliary phase MR image evaluation.

S11
Non-gated and non-enhanced MR Angiography of the Hand using enhanced acceleration selective arterial spin labeling (eAccASL)
Misaki Saito1, Shuhei Shibukawa1, Natsuo Konta1, Takuya Hara2, Takakiyo Nomura2, Makoto Obara3, Isao Muro1, and Tetsu Niwa2

1radiological technology, Tokai university hospital, Isehara, Japan, 2Tokai University School of Medicine, Isehara, Japan, 3Philips Japan, Tokyo, Japan

This study was conducted to optimize the enhanced Acceleration-Selective Arterial Spin Labeling (eAccASL) for non-gated hand MRA. The MRA images obtained using four acceleration encoding (AENC) were assessed by visual evaluation for arterial depiction and venous contamination. The blood flow velocity obtained by phase-contrast cine was compared with the visual evaluation. It was found that the smaller the AENC (i.e. stronger motion sensitize gradients), the higher venous contamination and higher arterial visualization. The tendency of high visual evaluation was found in subjects with fast blood flow. The AENC of 0.5 or 1.0 was optimized for non-gated MRA of the hand.

S12
The Effect of Enlarging Shim Volume on B0 homogeneity of MRS Voxel on 7T
Huijun Liao1, Eduardo Jorge Uribe Coello1, Wufan Zhao1, Han Sam Jiang1, and Alexander Lin1

1Center for Clinical Spectroscopy, Brigham and Women's Hospital, Boston, MA, United States

B0 homogeneity is important for clinical spectroscopy but is highly region dependent and time consuming.  Enlarging shim volume could be a quick and easy way to improve B0 homogeneity in the clinical practice of spectroscopy and the goal of this study is test if this method is beneficial.  We used different methods to measure the potential improvement in B0 homogeneity in different brain regions.  While our results showed that increasing shim volumes did not improve spectral linewidths or data quality, we demonstrate a robust method of measuring B0 homogeneity in clinical spectroscopy.

S25
Differential Diagnosis of uterine leiomyoma pathological subtypes: A Conditional Inference Tree Model Based on MRI-T2WI
Chao Wei1 and Jiangning Dong1

1Anhui provincial tumor hosptial, Hefei, China

The establishment  and  verification  of  conditional  inference  tree model based on based on the MRI-T2WI radiomics has high clinical value in the identification of three common pathological subtypes of uterine leiomyoma. 

S30
Depicting capsular injury and disc tears of the sternoclavicular joint with the use of direct MRI arthrography
Helen Harvey1

1MRI, Cambridge University Hospitals, Cambridge, United Kingdom

Advances in technology in MRI have allowed for the improved spatial resolution of small joints like the sternoclavicular joint (SCJ). We have shown that through the use of arthrography and MRI we can provide better visualisation of SCJ anatomy, disc tears and other pathologies. Helping to increase knowledge and greatly improve treatment and surgical planning options for the patient.

This presentation aims to understand the techniques for MRI arthrography of the SCJ, review anatomy demonstrated on SCJ arthrography and demonstrate common pathologies of the SCJ.


S39
A Single Breath-Hold Acquisition of Three-Dimensional T1 Mapping Using Look Locker sequence for Assessing Crohn Disease: A Phantom Study
Daisuke Morimoto-Ishikawa1,2, Tomoko Hyodo3, Shigeyoshi Saito2, Yu Ueda4, Masato Ohmi2, and Kazunari Ishii3

1Radiology Center, Kindai University Hospital, Osaka-Sayama, Japan, 2Department of Medical Physics and Engineering, Osaka University Graduate School of Medicine, Suita, Japan, 3Department of Radiology, Kindai University, Osaka-Sayama, Japan, 4Philips Japan, Tokyo, Japan

We investigated the single breath-hold three-dimensional (3D) Look-Locker (LL) sequence in nine different concentrations phantoms, which can be used to evaluate Crohn's disease (CD). Percentage errors between T1 relaxation time obtained by varying inversion recovery pulse interval and recovery period in the LL sequence and T1 relaxation time obtained by the Inversion Recovery sequence were calculated. With the combination of inversion recovery pulse interval of 7000ms and recovery period of 4000ms, the LL sequence can calculate T1 relaxation time within 10% percentage errors in the fastest imaging time of 21 seconds.

S41 Detection of Sacroiliac Joint Lesions in Axial Spondyloarthritis:Utility of Synthetic MRI
Ke Zhang1 and Guobin Hong2

1Radiology, The Fifth Affiliated Hospital,Sun Yat-sen University, Zhuhai, China, 2Radiology, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, China

The current diagnosis of the sacroiliac joint lesions with axSpA is most concentrated on qualitative or semi-quantitative methods.There is an urgent need for a quantitative method that can objectively and accurately evaluate the severity of the disease.Synthetic MRI (MAGiC) can generate multiple contrast images and quantitative maps simultaneously based on the same scan.To our knowledge,this study is the first to investigate the potential practicality of synthetic MRI for assessing sacroiliac joint lesions of participants with axSpA.In this study we hypothesized that synthetic MRI could be used for the qualitative and quantitative diagnosis of sacroiliac joints lesions of participants with axSpA. 

S74
Optimization of Radial K-space Sampling Techniques for a Comprehensive Motion-free Cervical Spine MRI Protocol
Brian Johnson1, Jonathan Chia1, Dave Hitt1, Rob Lay1, Tom Lowe1, Michael Pawlak1, John Penatzer1, James Snicer1, Marcie Stopchinski1, Gregory Thomas1, Kristen Williams1, and Paul Worthington1

1Philips Healthcare, Gainesville, FL, United States

Consistent high-quality magnetic resonance imaging (MRI) of the cervical spine still remains challenging because of the inherent small anatomical structures and degradation of image quality due to motion artifacts1.  Motion artifacts can arise from several sources including swallowing, respiration, cerebrospinal fluid (CSF) pulsation, blood flow, and bulk patient movement.  MRI of the cervical spine is one the highest performed exams globally.  Here we present a complete cervical spine MRI protocol utilizing 2D and 3D radial k-space sampling techniques which are inherently motion insensitive to increase image quality.  

S78
Diffusion: What is it and Why it is so Important in MR imaging
Gail H Kohls1, Robert Shih2, J Kevin Demarco2, and Maureen Hood2

1Radiology, USU/WRNMMC, MIDDLETOWN, MD, United States, 2Radiology, WRNMMC, Bethesda, MD, United States

The concepts behind diffusion imaging are complicated. As Technologist/Radiographers we use these finished pulse sequences in our daily work, but we do not always have the background information of how each sequence is developed and why it is an important part of the imaging we perform. This abstract is an attempt give the Technologist/Radiographer a better understanding of the key concepts of diffusion and how the diffusion sequences such as Diffusion Weighted Imaging (DWI) and Diffusion Tensor Imaging (DTI) measure water movement.

S80 A finding of Female Adnexal Tumour of probable Wolffian Origin (FATWO) on magnetic resonance imaging and histology - a rare neoplasm: Case report
Petronella Samuels1, Paul Scholtz2, Judith Whittaker3, and Sally Candy4

1Cape Universities Body Imaging Centre, University of Cape Town, Cape Town, South Africa, 2Department of Radiology, Morton & Partners Radiology, Cape Town, South Africa, 3Anatomical Pathology, Lancet Laboratories, Cape Town, South Africa, 4Division of Diagnostic Radiology, Groote Schuur Hospital and University of Cape Town, Cape Town, South Africa

We present the MRI and histological findings in a case of Female Adnexal Tumour of Wolffian Origin (FATWO) / WAT (Wolffian Adnexal Tumour), a rare adnexal neoplasm. This mass, located in the right broad ligament demonstrated diffusely low signal intensity on both T2WI and T1WI, peripheral restriction on DWI, peripheral enhancement and central hypo-enhancement post Gadolinium. An awareness of this condition and its MRI findings will ensure that appropriate immunohistochemical staining is performed. The presence of restriction may be helpful in predicting tumour behaviour, surgical approach and postoperative management.

 



SMRT Poster Presentations: Research

SMRT Posters
 SMRT

S5
MRI Safety for Leave-on Powdered Hair Thickeners: Measurement of Deflection Force and MRI Artifact
Norio Hayashi1, Akio Ogura1, Atsuya Fuju2, Tomokazu Takeuchi3, Yusuke Sato4, Maiko Hashimoto5, and Masahiko Takahashi5

1Radiological Technology, Gunma Prefectural College of Health Sciences, Maebashi, Japan, 2Radiology, Kiryu Kosei General Hospital, Kiryu, Japan, 3Graduate School of Radiological Technology, Gunma Prefectural College of Health Sciences, Maebashi, Japan, 4Radiology, Gunma University Hospital, Maebashi, Japan, 5Isesaki Municipal Hospital, Isesaki, Japan

The purpose of this study was to evaluate the attraction force and image artifacts of 17 different leave-on powdered hair thickeners from 7 vendors. Displacement force was measured by the ASTM F2052, and MRI artifact was estimated by the ASTM F2052. There were some types of leave-on powdered hair thickener that do contain magnetic materials. They were highly susceptible to mechanical effects and will cause more image artifacts, so it must be removed before the examination.

S7
Optimized 3D ultrashort TE protocol for lung imaging
CHIKARA NODA1, Chia Ying Liu2, Jason Ortman1, Bharath Venkatesh Ambale3, Webster Stayman4, Yoshimori Kassai5, and Joao A.C. Lima1

1Cardiology, Johns Hopkins University, Baltimore, MD, United States, 2Canon Medical Research, Cleveland, OH, United States, 3Radiology, Johns Hopkins University, Baltimore, MD, United States, 4Biomedical Engineering, Johns Hopkins University, Baltimore, MD, United States, 5Canon Medical Systems Corporation, Otawara, Japan

3D radial Ultrashort echo time sequence is a promising technique for lung imaging but the protocol has not been optimized. We examined the parameters including number of trajectories and flip angles using a lung phantom. In-vivo images were obtained and evaluated based on the parameters optimized in the phantom study. UTE acquisition in axial rather than coronal direction produced better quality of images. Breath holding acquisition may be an option in case patients cannot tolerate long scan time.

S19 Optimizing dark blood late gadolinium enhancement in cardiac magnetic resonance imaging.
Hannah Bergman1, Alaine Berry1, and Ben Statton1

1MRC, Imperial College, London, United Kingdom

The dark blood late gadolinium enhancement technique has shown improved delineation of sub-endocardial infarcts by nulling both the blood pool and the normal myocardium. Optimal image quality and consistency depends on a number of factors, including gadolinium dose and the delay time before imaging. In this study we sought to determine whether gadolinium dose and delay time before imaging, affected the nulling of the blood pool and myocardium.

S20
Quantitative evaluation of metal artifacts in 3-T MRI by using Blind/Referenceless Image Spatial Quality Evaluator (BRISQUE): a phantom study
Wakiko Tani1, Yutaka Katayama2, Tomoaki Yamakawa1, Shintaro Horii1, Ryuji Shimada1, Yuichiro Somiya1, and Akiko Kusaka1

1Center for Radiology and Radiation Oncology, Kobe University Hospital, Kobe, Japan, 2Division of Radiological Technology, Osaka City University Hospital, Osaka, Japan

No-reference image quality assessment (NR-IQA) model called Blind/Referenceless Image Spatial Quality Evaluator (BRISQUE) is one of the objective evaluations of images. To investigate whether BRISQUE can be used to quantify artifacts on MRI images, we compared the BRISQUE score with the visual score. The BRISQUE score was reduced and the visual score was improved by increasing bandwidths from 51 kHz to 307 kHz. Pearson correlation coefficient was 0.7576 and BRISQUE score was associated with the visual score (P < .05). This study suggests that BRISQUE can quantitatively evaluate metal artifacts.

S21
Compressed Sensing for Turbo Spin-echo Diffusion-weighted Imaging: Influence of Denoising Level on the Signal Intensity and Apparent Diffusion Coefficient Values in Cervical Cancer
Yuichiro Somiya1, Yoshiko Ueno2, Shintaro Horii1, Ryuji Shimada1, Keitaro Sofue2, Naoki Yoshida1, Wakiko Tani1, Akiko Kusaka1, and Takamichi Murakami2

1Center of Radiology and Radiation Oncology, kobe university hospital, kobe, Japan, 2Department of Radiology, Kobe University Graduate School of Medicine, kobe, Japan

This study evaluated the effect of denoising level on signal intensity (SI) and apparent diffusion coefficient (ADC) values of diffusion-weighted imaging using the single-shot turbo spin-echo sequence (TSE-DWI) with compressed sensing (CS) in cervical cancer. As the denoising level increased, the SI of cervical cancer tended to decrease, and the ADC values tended to increase on TSE-DWI with CS. Nevertheless, at each denoising level, the ADC values of cervical cancer were significantly lower than those of normal uterine cervix.

S31
Comparison of cardiac T1 mapping on a high-performance 0.55T scanner and a conventional 1.5T scanner
Christine Mancini1, W. Patricia Bandettini1, Peter Kellman1, Hui Xue1, and Adrienne E. Campbell-Washburn1

1NHLBI, National Institutes of Health, Bethesda, MD, United States

This abstract is a comparison of native and post contrast T1 mapping and ECV of the myocardium using a conventional 1.5T scanner and a high-performance 0.55T scanner.

S34
Effects of image quality deterioration and data shortage on automatic white matter bundle segmentation by diffusion magnetic resonance imaging
Yuichi Suzuki1, Tsuyoshi Ueyama1, Takahiro Iwasaki1, Jiro Sato1, Hideyuki Iwanaga1, and Osamu Abe1

1Department of Radiology, THe University of Tokyo Hospital, Tokyo, Japan

We investigated the effect of image quality deterioration and data shortage of DWI on automatic white matter bundle segmentation. We set the gold standard (GS) data without SMS and MPG = 64 axes. Two kinds of comparisons were made in comparison with GS data. The one was with/without the SMS, and the other eliminated some acquired data from GS. We analyze the data only from the first 8, 16, 32 and 48 axes of MPG in the GS. There was almost no difference between SMS of 2 and 3. For MPG, 16 axes provided results comparable to the GS.

S44
Optimization of Variable TI 4D ultrashort TE MR Angiography: A Numerical Simulation and Phantom Study
Toshiya Akatsu1, Haruyuki Fukuchi2,3,4, Kei Fukuzawa4, Nao Takano1, Yutaka Ikenouchi3, Michimasa Suzuki3, Kohji Kamagata3, Akihiko Wada3, Osamu Abe2, and Shigeki Aoki3

1Department of Radiology, Juntendo University Hospital, Tokyo, Japan, 2Department of Radiology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan, 3Department of Radiology, Juntendo University Graduate School of Medicine, Tokyo, Japan, 4Department of Radiology, Toranomon Hospital, Tokyo, Japan

We implemented the new Variable TI method to multi-phase ASL 4D UTE-MRA in order to improve the visibility of hemodynamic flow. We performed a numerical simulation and a phantom study to find the optimized condition. It was found that a 50 % reduction of TI steps increases 50 % of signal from the flow volume without impairment of structural information.

S59
Assessing the reproducibility of semi-automated segmentation methods on post-operative T1 post contrast and FLAIR MRI of GBM.
Olga V Fadeeva Da Costa1,2, Shah Islam2,3, Mark M Boubnovski3, Eric Aboagye3, and Adam D Waldman4,5

1Department of Surgery & Cancer, Cancer Imaging Centre, Hammersmith Campus, Imperial College, London, United Kingdom, 2Imaging Department, MRI Unit, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom, 3Department Of Surgery & Cancer, Cancer Imaging Centre, Hammersmith Campus, Imperial College, London, United Kingdom, 4Department of Brain Sciences, Hammersmith Campus, Imperial College, London, United Kingdom, 5Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom

Glioblastoma (GBM) account for ~70% of adult primary brain tumours.  Interrogation of post-operative disease residuum and peritumoral microenvironment is necessary for imaging biomarker development. This involves accurate delineation and segmentation of these particular regions of interest.  A total of 35 post-operative T1 post contrast and T2 FLAIR MRI’s underwent segmentation by two independent readers. There was poor inter reader reproducibility in segmentations of disease residuum on post contrast T1 images, although this improved was higher for on segmentation of abnormal regions on FLAIR.  Strong intra reader reproducibility suggests systematic error effects in identifying regions of interest. 

S60
Osteoporotic vertebral fracture analysis with intravoxel incoherent motion: a preliminary study
Hiroyuki Takashima1,2, Rui Imamura1, Tsuneo Takebayashi3, Yasuhisa Abe3, Izaya Ogon2, Hiroshi Oguma3, Yoshihiro Akatsuka1, and Toshihiko Yamashita2

1Division of Radiology and Nuclear Medicine, Sapporo Medical University Hospital, Sapporo, Japan, 2Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, Sapporo, Japan, 3Department of Orthopaedic Surgery, Sapporo Maruyama Orthopedic Hospital, Sapporo, Japan

The parameters of vertebral fracture (VF) and without fracture using intravoxel incoherent motion (IVIM) were analyzed. In addition, the usefulness of using IVIM for VF was investigated. The subjects of this study were 52 patients with VF in the acute phase. As a result, the ADC, D, and f of VF were significantly higher than without fracture. Meanwhile, the D* of VF were significantly lower than without fracture. In the future, new findings may be obtained by analyzing the IVIM parameters and VF prognosis.

S81
Optimizing a Motion Tracking Marker for Pediatric Patients
Kristina Mary Pelkola1,2, Onur Afacan1,2, Tess E. Wallace1,2, Pauline Connaughton1, Jenna McKay1, Joseph Zmuda1, Camilo Jaimes1, and Simon K. Warfield1,2

1Radiology, Boston Children's Hospital, Boston, MA, United States, 2Computational Radiology Laboratory, Boston Children's Hospital, Boston, MA, United States

Magnetic Resonance Imaging (MRI) can be challenging for pediatric patients due to the large tunnel and loud noises. Anxiety and fear can be sparked causing them to be uncooperative and unable to hold still [1,2]. These exams are often plagued with motion artifacts resulting in poor diagnostic image quality and a challenge for Radiologists to interpret [3]. The administration of sedation or anesthesia is costly, potentially harmful, and doesn't eliminate motion artifacts due to breathing and uncontrollable muscle spasms [4]. There is an unmet need for alternative methods to enable diagnostic imaging exams in the presence of motion.  

S90
Deep Inspiration Breath-Hold Radiotherapy does not induce MRI detectable LV functional and structural changes in patients with left-sided breast cancer – A six months follow-up
Xin Dong1,2, Arnold Ng3,4, Sharon Watson5, Harish Sharma5, Graham Galloway1,2,6, and Margot Lehman5

1Queensland University of Technology, Brisbane, Australia, 2Translational Research Institute, Woolloongabba, Australia, 3Cardiology, Princess Alexandra Hospital, Brisbane, Australia, 4University of New South Wales, Sydney, Australia, 5Radiation Oncology, Princess Alexandra Hospital, Brisbane, Australia, 6The University of Queensland, St Lucia, Australia

The usefulness of T1 and ECV mappings in the context of radiation cardiotoxicity has yet to be studied. In the current study, we conducted a longitudinal CMR study on 30 females with left-sided breast cancer before and after Deep Inspiration Breast Hold (DIBH) radiotherapy (RT). The results showed patients who were treated with DIBH RT had no CMR detectable functional or structural myocardial changes 6 months following RT treatment. This has important implications on the long-term cardiac health of the growing number of women who are surviving or living with breast cancer.

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7T Knee MRI: Clinical Benefits and Challenges
Kevin Epperson1, Karla Epperson1, Garry Gold2, and Feliks Kogan3

1Radiology School of Medicine, Stanford University, Stanford, CA, United States, 2Radiology, Stanford Univeristy, Stanford, CA, United States, 3Radiology - SOM, Stanford Univeristy, Stanford, CA, United States

Diagnostic MRI scanning of the knee at 3T offers multiple contrasts and definition of anatomical structures, presenting pathology, and allows quantitative performance methods.  MRI scanning at 7T of the knee presents challenges, however the ultra high field system offers improved resolution and SNR for visualization of small morphological changes and translation of quantitative methods when these challenges are satisfied.