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7T MRI Reveals Abnormal Iron Deposition and Microstructure in Premanifest and Manifest Huntingtons Disease

Author:Jingwen Yao  Melanie Morrison  Angela Jakary  Sivakami Avadiappan  Julia Glueck  Theresa Driscoll  Michael Geschwind  Alexandra Nelson  Duan Xu  Christopher Hess  Janine Lupo  

Session Type:Power Pitch  

Session Date:Tuesday, 06 June 2023  

Session Name:Pitch: Neurodegeneration in Human & Animal Models  

Program Number:0574  

Room Session:Power Pitch Theatre 1  

Institution :University of California, San Francisco  

Diffusion MRI reveals rescue of structural changes in a mouse model of Huntingtons disease by mutant Huntingtin lowering

Author:Joëlle van Rijswijk  Nicholas Vidas-Guscic  Johan Van Audekerke  Tamara Vasilkovska  Dorian Pustina  Haiying Tang  Roger Cachope  Deanna Marchionini  Ignacio Munoz-Sanjuan  Annemie Van der Linden  Mohit Adhikari  Marleen Verhoye  

Session Type:Power Pitch  

Session Date:Tuesday, 06 June 2023  

Session Name:Pitch: Neurodegeneration in Human & Animal Models  

Program Number:0575  

Room Session:Power Pitch Theatre 1  

Institution :CHDI Management/CHDI Foundation  University of Antwerp  

A longitudinal study of cerebral metabolite alteration in the developmental monkey brain with Huntington's disease

Author:Chunxia Li  Xiaodong Zhang  

Session Type:Power Pitch  

Session Date:Tuesday, 06 June 2023  

Session Name:Pitch: Neurodegeneration in Human & Animal Models  

Program Number:0576  

Room Session:Power Pitch Theatre 1  

Institution :Emory University  

Ultra-high spatial resolution for ex-vivo structural brain MRI

Author:Alireza Abaei  Stefano Antonucci  Jelena Scekic-Zahirovic  Florian olde Heuvel  Francesco Roselli  Volker Rasche  

Session Type:Power Pitch  

Session Date:Tuesday, 06 June 2023  

Session Name:Pitch: Neurodegeneration in Human & Animal Models  

Program Number:0577  

Room Session:Power Pitch Theatre 1  

Institution :German Center for Neurodegenerative Diseases (DZNE)  University of Ulm  

A Method for Detection of Subtle Blood-Brain Barrier Disruption using Non-Contrast MR Fingerprinting

Author:Emma Thomson  Elizabeth Powell  Claudia Gandini Wheeler-Kingshott  Geoff Parker  

Session Type:Power Pitch  

Session Date:Tuesday, 06 June 2023  

Session Name:Pitch: Neurodegeneration in Human & Animal Models  

Program Number:0578  

Room Session:Power Pitch Theatre 1  

Institution :NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation  University College London  UCL Queen Square Institute of Neurology, Faculty of Brain Sciences  University of Pavia  Bioxydyn Limited  IRCCS Mondino Foundation  

Investigating application of multi-echo, multi-delay arterial spin labeling (ASL) to study endothelial exchange of water

Author:Swati Levendovszky  Lena Vaclavu  Jaqueline Flores  Elaine Peskind  Jeffrey Iliff  Matthias van Osch  

Session Type:Power Pitch  

Session Date:Tuesday, 06 June 2023  

Session Name:Pitch: Neurodegeneration in Human & Animal Models  

Program Number:0579  

Room Session:Power Pitch Theatre 1  

Institution :Leiden University Medical Center  University of Washington School of Medicine  VA Puget Sound  

ASL spatial coefficient of variance predicts increased white matter hyperintensities volume over time in cognitively unimpaired subjects

Author:Beatriz Padrela  Lyduine Collij  Luigi Lorenzini  Silvia Ingala  Carole Sudre  Pieter Jelle Visser  Anouk den Braber  Frederik Barkhof  Jan Petr  Henk Mutsaerts  

Session Type:Power Pitch  

Session Date:Tuesday, 06 June 2023  

Session Name:Pitch: Neurodegeneration in Human & Animal Models  

Program Number:0580  

Room Session:Power Pitch Theatre 1  

Institution :Alzheimer Center  Amsterdam UMC  Helmholtz-Zentrum Dresden-Rossendorf  Centre for Medical Image Computing (CMIC)  

Region-specific characteristics of brain oxygen extraction fraction: relationships to aging and white matter hyperintensities

Author:Jie Song  Wen Shi  Kaisha Hazel  George Pottanat  Ebony Jones  Cuimei Xu  Doris Lin  Sevil Yasar  Marilyn Albert  Hanzhang Lu  Dengrong Jiang  

Session Type:Power Pitch  

Session Date:Tuesday, 06 June 2023  

Session Name:Pitch: Neurodegeneration in Human & Animal Models  

Program Number:0581  

Room Session:Power Pitch Theatre 1  

Institution :Johns Hopkins School of Medicine  Johns Hopkins University School of Engineering  Johns Hopkins University School of Medicine  

Chronic stress impacts energy metabolism and triggers motor neuropathy in an Optineurin knockout mouse model

Author:Bedaballi Dey  Dipak Roy  Sumana Chakravarty  Ghanshyman Swarup  Arvind Kumar  Anant Patel  

Session Type:Power Pitch  

Session Date:Tuesday, 06 June 2023  

Session Name:Pitch: Neurodegeneration in Human & Animal Models  

Program Number:0582  

Room Session:Power Pitch Theatre 1  

Institution :CSIR-Centre for Cellular & Molecular Biology (CCMB)  CSIR-Indian Institute of Chemical Technology (IICT)  Academy of Scientific and Innovative Research (AcSIR)  

MRI detects macro- and microstructural changes to normal brain tissue following hemi-brain radiotherapy

Author:Ben Dickie  Duncan Forster  Abigail Bryce-Atkinson  Izabelle Lövgren  Azadeh Abravan  Marcel van Herk  Kaye Williams  

Session Type:Power Pitch  

Session Date:Tuesday, 06 June 2023  

Session Name:Pitch: Neurodegeneration in Human & Animal Models  

Program Number:0583  

Room Session:Power Pitch Theatre 1  

Institution :Division of Cancer Sciences, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK  Division of Informatics, Imaging and Data Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK  Divis  

Quantitative correlations of propagator metrics with phosphorylated tau and astrogliosis in chronic traumatic encephalopathy

Author:Mihika Gangolli  Sinisa Pajevic  Elizabeth Hutchinson  Joong Hee Kim  Dan Benjamini  Peter Basser  

Session Type:Power Pitch  

Session Date:Tuesday, 06 June 2023  

Session Name:Pitch: Neurodegeneration in Human & Animal Models  

Program Number:0584  

Room Session:Power Pitch Theatre 1  

Institution :Center for Neuroscience and Regenerative Medicine  National Institutes of Health  University of Arizona  The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.  

Shared and differed functional connectivity abnormalities for default mode network in mild cognitive impairment and Alzheimers disease

Author:Yaxuan Wang  Fenghua Long  Qiyong Gong  Su Lui  Fei Li  

Session Type:Power Pitch  

Session Date:Tuesday, 06 June 2023  

Session Name:Pitch: Neurodegeneration in Human & Animal Models  

Program Number:0585  

Room Session:Power Pitch Theatre 1  

Institution :Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan, P.R. China.  

Distinct patterns of microstructural changes in mouse models of ALS/FTD with mutations in Tardbp, Fus and C9orf72

Author:Aurea Martins Bach  Cristiana Tisca  Mohamed Tachrount  Carmelo Milioto  Mireia Carcolé  Shoshana Spring  Remya Nair  Thomas Cunningham  Elizabeth Fisher  Adrian Isaacs  Brian Nieman  Jason Lerch  Karla Miller  

Session Type:Power Pitch  

Session Date:Tuesday, 06 June 2023  

Session Name:Pitch: Neurodegeneration in Human & Animal Models  

Program Number:0586  

Room Session:Power Pitch Theatre 1  

Institution :Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, University College London  Department of Physiology, Anatomy and Genetics, University of Oxford  Mouse Imaging Centre, The Hospital for Sick Children  MRC Prion Unit and Instit  

The interaction between first-episode schizophrenia and age based on gray matter volume and its molecular analysis: A multimodal MRI study

Author:Jingli Chen  Yarui Wei  Kangkang Xue  Jingliang Cheng  

Session Type:Power Pitch  

Session Date:Tuesday, 06 June 2023  

Session Name:Pitch: Neurodegeneration in Human & Animal Models  

Program Number:0587  

Room Session:Power Pitch Theatre 1  

Institution :the first affiliated hospital of zhengzhou university  Magnetic Resonance Imaging  

S-EBM: generalising event-based modelling of disease progression for simultaneous events

Author:Christopher Parker  Neil Oxtoby  Daniel Alexander  Hui Zhang  

Session Type:Power Pitch  

Session Date:Tuesday, 06 June 2023  

Session Name:Pitch: Neurodegeneration in Human & Animal Models  

Program Number:0588  

Room Session:Power Pitch Theatre 1  

Institution :Centre for Medical Image Computing, Department of Computer Science, UCL, London, UK  

Multicompartment Imaging of the Brain Using a Comprehensive MR Imaging Protocol

Author:James Lo  Eric Chang  Jiang Du  Graeme Bydder  Yajun Ma  

Session Type:Power Pitch  

Session Date:Tuesday, 06 June 2023  

Session Name:Pitch: Neurodegeneration in Human & Animal Models  

Program Number:0589  

Room Session:Power Pitch Theatre 1  

Institution :University of California San Diego  Veteran Affairs San Diego Healthcare System  

Exploring the sensitivity of the NODDI model in detecting aging-related differences in gray and white matter in cognitively intact adults

Author:Jennapher Lingo VanGilder  Leslie Baxter  Leland Hu  YuXiang Zhou  Richard Caselli  Kurt Schilling  Scott Beeman  

Session Type:Power Pitch  

Session Date:Tuesday, 06 June 2023  

Session Name:Pitch: Neurodegeneration in Human & Animal Models  

Program Number:0590  

Room Session:Power Pitch Theatre 1  

Institution :Arizona State University  Mayo Clinic  Vanderbilt University  

Brain and cervical spinal cord myelination and age-related changes in adulthood: a preliminary study based on ihMTsat and T1 relaxometry mapping

Author:Arash Forodighasemabadi  Lucas Soustelle  Olivier Girard  Thomas Troalen  Jean-Philippe Ranjeva  Guillaume Duhamel  Virginie Callot  

Session Type:Power Pitch  

Session Date:Tuesday, 06 June 2023  

Session Name:Pitch: Neurodegeneration in Human & Animal Models  

Program Number:0591  

Room Session:Power Pitch Theatre 1  

Institution :Aix-Marseille Univ, CNRS, CRMBM  Siemens Healthcare SAS  APHM, Hopital Universitaire Timone, CEMEREM  Aix-Marseille Univ, Université Gustave Eiffel, LBA  iLab-Spine International Associated Laboratory, Montreal, Canada  

Are fMRI findings on emotional aging affected by cerebrovascular aging?

Author:Loretta Donaldson  Parimal Joshi  Lincoln Kartchner  Sara Akar  Peiying Liu  

Session Type:Power Pitch  

Session Date:Tuesday, 06 June 2023  

Session Name:Pitch: Neurodegeneration in Human & Animal Models  

Program Number:0592  

Room Session:Power Pitch Theatre 1  

Institution :University of Maryland, Baltimore  

MR Imaging Deep Brain Stimulation of the Nucleus Basalis Meynert Restored Cognitive Function in Alzheimers Disease Model

Author:Ching-Wen Chang  Yi-Chen Lin  Chiung-Yuan Ko  Yu-Chun Lo  Ting-Chieh Chen  Ssu-Ju Li  Mu-Hua Wang  Tsai-Yu Cho  Sheng-Huang Lin  You-Yin Chen  

Session Type:Power Pitch  

Session Date:Tuesday, 06 June 2023  

Session Name:Pitch: Neurodegeneration in Human & Animal Models  

Program Number:0593  

Room Session:Power Pitch Theatre 1  

Institution :Buddhist Tzu Chi Medical Foundation  National Yang Ming Chiao Tung University  Taipei Medical University  Academia Sinica  Tzu Chi University