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Application of a novel 13C hyperpolarized metabolic tracer for ?-Glutamyl transferase activity in vivo tumor xenograft

Author:Tomohiro Seki  Marino Itoda  Shun Kishimoto  Kazu Yamamoto  Yoichi Takakusagi  Jeffery Brender  Ronja Malinowski  Tatsuya Nishihara  Hikari Yoshihara  Hiroshi Nonaka  Keita Saito  Nobu Oshima  Jan Ardenkjaer-Larsen  James Mitchell  Murali Krishna   Sando  

Author Institution:DTU  EPFL  NIH  QST  UT  

Session Type:Traditional Poster  

Session Date:Thursday, 21 June 2018  

Session Time:13:15  

Session:Hyperpolarised MR  

Program Number:3052  

Presentation Time:

Room Number:Exhibition Hall 3052-3074  

Computer Number:

Considerations for Spin Order Transfer to 13C-labeled pyruvate precursors by Parahydrogen-induced Polarization for in vivo applications

Author:Neil Stewart  Mitsushi Tomohiro  Yoshiki Uchio  Kensuke Takoshima  Shingo Matsumoto  

Author Institution:Hokkaido University  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Hyperpolarisation: Technical Developments  

Program Number:3573  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 21  

Developing a therapeutic strategy for a glycolytic cancer model by monitoring on-target in vivo efficacy of a newly developed LDH inhibitor using hyperpolarized 13C Magnetic Resonance Imaging

Gadoxetic acid-enhanced dynamic MR imaging using optimized integrated combination with parallel imaging and compressed sensing technique.

Hepatobiliary phase imaging using optimized integrated combination with parallel imaging and compressed sensing technique.

Hyperpolarized [1-13C]pyruvate MRS reveals early-phase transition of energy metabolism in multicellular spheroid tumors

Author:Yoichi Takakusagi  Kaori Takakusagi  Kaori Inoue  Kazuhiro Ichikawa  

Author Institution:Kyushu University  Nagasaki International Unversity  National Institute of Radiological Sciences, QST  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:17:15  

Session:Hyperpolarisation: Applications  

Program Number:3720  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 48  

In vivo characterization of glucose metabolism in pancreatic cancer xenografts.

Author:Shun Kishimoto  Jeffrey Brender  Tomohiro Seki  Ayano Enomoto  Kazutoshi Yamamoto  Murali Krishna  

Author Institution:NCI  

Session Type:Electronic Poster  

Session Date:Tuesday, 19 June 2018  

Session Time:08:15  

Session:MRS Applications  

Program Number:3899  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 108  

Magnetic resonance cholangiopancreatography using optimized integrated combination with parallel imaging and compressed sensing technique compared with conventional MRCP.

Metabolic imaging of glioblastoma using hyperpolarized 13C-MRI - glycolytic metabolism in cancer stem cell-like cells.

Author:Tatsuya Kawai  Jeffery Brender  Kevin Camphausen  Murali Krishna  

Author Institution:National Cancer Institute, NIH  

Session Type:Traditional Poster  

Session Date:Monday, 18 June 2018  

Session Time:08:15  

Session:MRS Animal Studies  

Program Number:1366  

Presentation Time:

Room Number:Exhibition Hall 1361-1368  

Computer Number:

Monitoring effect of rapamycin on pyruvate metabolism in SCC tumor using hyperpolarized 13C-MRI

Author:Keita Saito  Shingo Matsumoto  Yoichi Takakusagi  Masayuki Matsuo  Hellmut Merkle  James Mitchell  Murali Krishna  

Author Institution:National Cancer Institute  National Institute of Neurological Disorder and Stroke  

Session Type:Traditional Poster  

Session Date:Thursday, 21 June 2018  

Session Time:13:15  

Session:Hyperpolarised MR  

Program Number:3069  

Presentation Time:

Room Number:Exhibition Hall 3052-3074  

Computer Number:

Multimodal Characterization of In Vivo Metabolic Activities with Hyperpolarized 13C MRI, 18F-FDG PET, and EPR Imaging in Pancreatic Ductal Adenocarcinoma Tumors

Author:Kazutoshi Yamamoto  Tomohiro Seki  Shun Kishimoto  Nallathamby Devasahayam  Nobu Oshima  Stephen Adler  Elaine Jagoda  Keita Saito  Jeffrey Brender  Peter Choyke  James Mitchell  Murali Krishna  

Author Institution:National Institutes of Health  

Session Type:Oral  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Hyperpolarisation: Probe Development & Clinical Application  

Program Number:0279  

Presentation Time:17:39  

Room Number:S04  

Computer Number:

Non-invasive redox molecular imaging of atopic dermatitis using in vivo dynamic nuclear polarization MRI

Author:Fuminori Hyodo  Hinako Eto  Gaku Tsuji  Masutaka Furue  Masayuki Matsuo  

Author Institution:Gifu University  Kyushu University  

Session Type:Traditional Poster  

Session Date:Thursday, 21 June 2018  

Session Time:13:15  

Session:Hyperpolarised MR  

Program Number:3068  

Presentation Time:

Room Number:Exhibition Hall 3052-3074  

Computer Number:

PET by MRI: Glucose Imaging by 13C MRS by Noise Suppression through Tensor Decomposition Rank Reduction

Author:Jeffrey Brender  Shun Kishimoto  Hellmut Merkle  Galen Reed  Ralph Hurd  Albert Chen  Jan Ardenkjaer-Larsen  Jeeva Munasinghe  Keita Saito  Tomohiro Seki  Nobu Oshima  Kazu Yamamoto  James Mitchell  Murali Krishna  

Author Institution:GE Healthcare  NIH/NCI  NIH/NINDS  Technical University of Denmark  

Session Type:Oral  

Session Date:Wednesday, 20 June 2018  

Session Time:16:15  

Session:Non-Proton MRS/MRI  

Program Number:0905  

Presentation Time:16:39  

Room Number:S02  

Computer Number:

Prostate Cancer: Defining Clinically Significant Disease

Author:Peter Choyke  

Author Institution:National Cancer Institute  

Session Type:Combined Educational & Scientific Session  

Session Date:Tuesday, 19 June 2018  

Session Time:08:15  

Session:Prostate Cancer: Current Gaps & Future Directions  

Program Number:

Presentation Time:08:15  

Room Number:S02  

Computer Number:

T1 mapping of the pancreas: correlation with HbA1c values

Author:Yoshifumi Noda  Satoshi Goshima  Yusuke Tsuji  Kimihiro Kajta  Yuta Akamine  Tomoyuki Okuaki  Masatoshi Honda  Hiroshi Kadohara  Hiroshi Kawada  Nobuyuki Kawai  Yukichi Tanahashi  Masayuki Matsuo  

Author Institution:Gifu University  Kyoto Prefectural University of Medicine  Philips Healthcare  

Session Type:Oral  

Session Date:Wednesday, 20 June 2018  

Session Time:13:45  

Session:Pancreas/GI  

Program Number:0826  

Presentation Time:14:21  

Room Number:S05  

Computer Number:

Time-domain EPR imaging with slice selection

Author:Ayano Enomoto  Ken-ichiro Matsumoto  Shun Kishimoto  Shingo Matsumoto  Murali Krishna  Nallathamby Devasahayam  

Author Institution:Hokkaido University  National Institute of Radiological Sciences  National Institutes of Health  

Session Type:Traditional Poster  

Session Date:Monday, 18 June 2018  

Session Time:08:15  

Session:Spectroscopy: NMR & Other  

Program Number:1336  

Presentation Time:

Room Number:Exhibition Hall 1336-1345  

Computer Number: