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Hyperpolarized 13C MRSI detects immunomodulatory responses to dimethyl fumarate and fingolimod therapies in a model of multiple sclerosis

Author:Caroline Guglielmetti  Christian Cordano  Chloe Najac  Ari Green  Myriam Chaumeil  

Session Type:Oral  

Session Date:Monday, 05 June 2023  

Session Name:Imaging Inflammation Across Neurological Diseases  

Program Number:0024  

Room Session:714A/B  

Institution :C.J. Gorter Center for High Field MRI, Leiden University Medical Center  University of California San Francisco  

Free water diffusion volume fraction from NODDI suggests inflammation may drive decreased memory performance in Subjective Cognitive Decline

Author:Ryn Flaherty  Yu Sui  Mariana Lazar  

Session Type:Oral  

Session Date:Monday, 05 June 2023  

Session Name:Imaging Inflammation Across Neurological Diseases  

Program Number:0025  

Room Session:714A/B  

Institution :New York University Grossman School of Medicine  

Multiple Sclerosis (MS): High Contrast Visualisation of Abnormalities in Normal Appearing White Matter Using MASDIR Sequences

Author:Paul Condron  Haribalan Kumar  Samantha Holdsworth  Daniel Cornfeld  Graeme Bydder  

Session Type:Oral  

Session Date:Monday, 05 June 2023  

Session Name:Imaging Inflammation Across Neurological Diseases  

Program Number:0026  

Room Session:714A/B  

Institution :Auckland Bioengineering Institute  Matai Medical Research Institute  Univeristy of Auckland  University of California San Diego  GE Healthcare  

Neuroinflammation and amyloid deposition in the progression of mixed Alzheimer and vascular dementia

Author:Chunwei Ying  Peter Kang  Michael Binkley  Andria Ford  Yasheng Chen  Jason Hassenstab  Qing Wang  Jeremy Strain  John Morris  Jin-Moo Lee  Tammie Benzinger  Hongyu An  

Session Type:Oral  

Session Date:Monday, 05 June 2023  

Session Name:Imaging Inflammation Across Neurological Diseases  

Program Number:0027  

Room Session:714A/B  

Institution :Washington University School of Medicine  

Positron emission tomography with [ 18F]-DPA-714 unveils a smoldering component in most multiple sclerosis lesions driving disease progression

Author:Mariem Hamzaoui  Jeanne Garcia  Giacomo Boffa  Andrea Lazzarotto  Vito A G Ricigliano  Arya Yazdan Panah  Théodore Soulier  Celine Louapre  Benedetta Bodini  Bruno Stankoff  

Session Type:Oral  

Session Date:Monday, 05 June 2023  

Session Name:Imaging Inflammation Across Neurological Diseases  

Program Number:0028  

Room Session:714A/B  

Institution :Department of Neurology, Saint- Antoine Hospital, APHP, Paris, France  Sorbonne Université, Paris Brain Institute, ICM, CNRS, Inserm, Paris, France  Department of Neurology, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of  

Disruption to normal excitatory and inhibitory function within the medial prefrontal cortex in patients with IBD

Author:Jun Wang  Guangyao Liu  Kai Ai  Pengfei Zhang  Wenjing Huang  Jing Zhang  

Session Type:Oral  

Session Date:Monday, 05 June 2023  

Session Name:Imaging Inflammation Across Neurological Diseases  

Program Number:0029  

Room Session:714A/B  

Institution :Lanzhou University  Lanzhou University Second Hospital  Philips Healthcare  

Quantifying Cervical Spinal Cord Pathology of Multiple Sclerosis Patients Using Advanced MRI

Author:Osman Hatipoglu  Tsagkas Charidimos  Mario Ocampo-Pineda  Lester Melie-Garcia  Matthias Weigel  Po-Jui Lu  Muhamed Barakovic  Julien Cohen-Adad  Ludwig Kappos  Jens Kuhle  Cristina Granziera  

Session Type:Oral  

Session Date:Monday, 05 June 2023  

Session Name:Imaging Inflammation Across Neurological Diseases  

Program Number:0030  

Room Session:714A/B  

Institution :Université de Montréal  University Hospital Basel  University Hospital Basel and University of Basel  National Institutes of Health (NIH)  Polytechnique Montreal  Quebec AI Institute  

Iron accumulation and MRI iron contrast are not driven by amyloid plaques in posterior cortical atrophy

Author:Evgeniya Kirilina  Luke Edwards  Carsten Jäger  Tilo Reinert  Anna Jauch  Malte Brammerloh  Karl-Heinz Herrmann  Patrick Scheibe  Felix Büttner  Dennis Brückner  Gerald Falkenberg  Jürgen Reichenbach  Nikolaus Weiskopf  

Session Type:Oral  

Session Date:Monday, 05 June 2023  

Session Name:Imaging Inflammation Across Neurological Diseases  

Program Number:0031  

Room Session:714A/B  

Institution :Deutsches Elektronen-Synchrotron DESY  Jena University Hospital  Max Planck Institute for Human Cognitive and Brain Sciences  Leipzig University  Paul Flechsig Institute - Center of Neuropathology and Brain Research  

Regional Changes in Brain Viscoelasticity in Multiple Sclerosis Assessed with Three-Dimensional MR Elastography

Author:Ling Fang  Matthew Murphy  Sha Tan  Qiuxia Luo  Jingbiao Chen  Bingjun He  Jun Chen  Jonathan Scott  Kevin Glaser  Richard Murphy  Wei Qiu  Jin Wang  

Session Type:Oral  

Session Date:Monday, 05 June 2023  

Session Name:Imaging Inflammation Across Neurological Diseases  

Program Number:0032  

Room Session:714A/B  

Institution :Mayo Clinic  the Third Affiliated Hospital, Sun Yat-sen University  

Elevated free-water volume in the brains of HIV+ alcohol drinkers compared to HIV- drinkers as an indication of neuro-inflammation

Author:Teddy Salan  Varan Govind  Joseph Gullett  Eric Porges  Zhigang Li  Ronald Cohen  Robert Cook  

Session Type:Oral  

Session Date:Monday, 05 June 2023  

Session Name:Imaging Inflammation Across Neurological Diseases  

Program Number:0033  

Room Session:714A/B  

Institution :University of Florida  University of Miami  

Multimodal 9.4T MRI and Near-Infrared Spectroscopy shows reduced perfusion and abnormal oxidative metabolism in the EAE mouse model of MS

Author:Mada Hashem  A. Hamilton  Jeff Dunn  

Session Type:Oral  

Session Date:Monday, 05 June 2023  

Session Name:Imaging Inflammation Across Neurological Diseases  

Program Number:0034  

Room Session:714A/B  

Institution :University of Calgary  

Pathological Validation of Multiple Sclerosis Lesion Rims on Phase and Quantitative Susceptibility Mapping (QSM) images

Author:Kelly Gillen  Thanh Nguyen  Alexey Dimov  Emily Demmon  Ilhami Kovanlikaya  Francesca Bagnato  Dominick Romano  David Pitt  Susan Gauthier  Yi Wang  

Session Type:Oral  

Session Date:Monday, 05 June 2023  

Session Name:Imaging Inflammation Across Neurological Diseases  

Program Number:0035  

Room Session:714A/B  

Institution :Department of Neurology, TN Valley HealthCare VA Medical System  Department of Neurology, Weill Cornell Medicine  Department of Neurology, Yale School of Medicine  Department of Radiology, Weill Cornell Medicine  4Department of Neurology, Vanderbilt Unive  

Association between PET-MR imaging measures of blood-brain barrier leakage and immune cell activation in acute intracerebral hemorrhage

Author:Olivia Jones  Saffwan Mohamed  Rainer Hinz  Ben Dickie  Laura Parkes  Adrian Parry-Jones  

Session Type:Oral  

Session Date:Monday, 05 June 2023  

Session Name:Imaging Inflammation Across Neurological Diseases  

Program Number:0036  

Room Session:714A/B  

Institution :Northern Care Alliance NHS Foundation Trust  University of Manchester  Geoffrey Jefferson Brain Research Centre  

Brain Metabolite Concentrations of White Matter and Grey Matter in Perinatal HIV Infected Adults Using a Whole-Brain MR Spectroscopic Imaging

Author:Teddy Salan  Elizabeth Willen  Anai Cuadra  Sulaiman Sheriff  Andrew Maudsley  Varan Govind  

Session Type:Oral  

Session Date:Monday, 05 June 2023  

Session Name:Imaging Inflammation Across Neurological Diseases  

Program Number:0037  

Room Session:714A/B  

Institution :Univerity of Miami  University of Missouri-Kansas City School of Medicine  

Brain diffusion alterations in patients with COVID-19 pathology and neurological manifestations

Author:Anna Caroli  Serena Capelli  Angela Napolitano  Giulia Cabrini  Alberto Arrigoni  Giulio Pezzetti  Mattia Previtali  Luca Longhi  Rosalia Zangari  Ferdinando Lorini  Maria Sessa  Andrea Remuzzi  Simonetta Gerevini  

Session Type:Oral  

Session Date:Monday, 05 June 2023  

Session Name:Imaging Inflammation Across Neurological Diseases  

Program Number:0038  

Room Session:714A/B  

Institution :ASST Papa Giovanni XXIII  Istituto di Ricerche Farmacologiche Mario Negri IRCCS  University of Bergamo