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Deuterium magnetic resonance spectroscopy using 2H-pyruvate allows non-invasive in vivo imaging of TERT expression in brain tumors

Author:Georgios Batsios  Celine Taglang  Meryssa Tran  Anne Marie Gillespie  Joseph Costello  Sabrina Ronen  Pavithra Viswanath  

Session Type:Oral  

Session Date:Monday, 17 May 2021  

Topic:Cancer: Contrast Agents & MRS  

Session Name:Cancer: Contrast Agents & MRS  

Program Number:0018  

Room Session:Concurrent 2  

Institution:UCSF  

Deuterium metabolic imaging of tumor burden and response to therapy in mutant IDH gliomas in vivo

Hyperpolarized d-[1-13C]gluconolactone detects response to chemotherapy in brain tumors in vivo

Author:Georgios Batsios  Celine Taglang  Anne Marie Gillespie  Peder Larson  Sabrina Ronen  Pavithra Viswanath  

Session Type:Oral  

Session Date:Thursday, 20 May 2021  

Topic:Latest Advances in Hyperpolarized MRI  

Session Name:Latest Advances in Hyperpolarized MRI  

Program Number:0679  

Room Session:Concurrent 2  

Institution:UCSF  

A kinetic model to quantify 2-hydroxyglutarate when using hyperpolarized [1-13C]?-ketoglutarate to detect mutant IDH1 in low grade gliomas

MRS based biomarkers of IDH1 mutant glioma response to the BAY-1436032 IDH inhibitor