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Application of a novel 13C hyperpolarized metabolic tracer for ?-Glutamyl transferase activity in vivo tumor xenograft

Author:Tomohiro Seki  Marino Itoda  Shun Kishimoto  Kazu Yamamoto  Yoichi Takakusagi  Jeffery Brender  Ronja Malinowski  Tatsuya Nishihara  Hikari Yoshihara  Hiroshi Nonaka  Keita Saito  Nobu Oshima  Jan Ardenkjaer-Larsen  James Mitchell  Murali Krishna   Sando  

Author Institution:DTU  EPFL  NIH  QST  UT  

Session Type:Traditional Poster  

Session Date:Thursday, 21 June 2018  

Session Time:13:15  

Session:Hyperpolarised MR  

Program Number:3052  

Presentation Time:

Room Number:Exhibition Hall 3052-3074  

Computer Number:

Assessing ?-glutamyl transpeptidase activity in kidney using hyperpolarized ?-Glu-[1-13C]Gly

Author:Steffen Frank  Hikari Yoshihara  Marino Itoda  Shinsuke Sando  Rolf Gruetter  

Author Institution:EPFL  The University of Tokyo  University of Geneva  

Session Type:Traditional Poster  

Session Date:Thursday, 21 June 2018  

Session Time:13:15  

Session:Hyperpolarised MR  

Program Number:3066  

Presentation Time:

Room Number:Exhibition Hall 3052-3074  

Computer Number:

Detection of D-amino acid oxidase using hyperpolarized molecular probes

Author:Alice Radaelli  Hikari Yoshihara  Rolf Gruetter  

Author Institution:EPFL  

Session Type:Oral  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Hyperpolarisation: Probe Development & Clinical Application  

Program Number:0281  

Presentation Time:18:03  

Room Number:S04  

Computer Number:

Probing perturbed hepatic metabolism in bile-duct-ligated rats with hyperpolarized 13C pyruvate and arginine

Author:Hikari Yoshihara  Dmitri Firsov  Cristina Cudalbu  Rolf Gruetter  

Author Institution:Swiss Federal Institute of Technology, Lausanne (EPFL)  University of Lausanne  

Session Type:Power Pitch  

Session Date:Monday, 18 June 2018  

Session Time:13:45  

Session:Pitch: Molecular & Metabolic Imaging  

Program Number:0108  

Presentation Time:13:45  

Room Number:Power Pitch Theater A - Exhibition Hall  

Computer Number:

Probing perturbed hepatic metabolism in bile-duct-ligated rats with hyperpolarized 13C pyruvate and arginine

Author:Hikari Yoshihara  Dmitri Firsov  Cristina Cudalbu  Rolf Gruetter  

Author Institution:Swiss Federal Institute of Technology, Lausanne (EPFL)  University of Lausanne  

Session Type:Electronic Power Pitch Poster  

Session Date:Monday, 18 June 2018  

Session Time:14:45  

Session:Poster: Molecular & Metabolic Imaging  

Program Number:0108  

Presentation Time:13:45  

Room Number:Power Pitch Theater A - Exhibition Hall  

Computer Number:Plasma 7  

Probing renal pH and aminopeptidase N activity with hyperpolarized [1-13C]alaninamide

Author:Alice Radaelli  Hikari Yoshihara  Ryunosuke Hata  Shinsuke Sando  Rolf Gruetter  

Author Institution:EPFL  Kyushu University  The University of Tokyo  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Hyperpolarisation: Technical Developments  

Program Number:3566  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 14