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Early MR-detectable biomarkers of mutant IDH inhibition in patient-derived low-grade gliomas in vivo

Hyperpolarized [1-13C]/[5-13C] glutamate as a metabolic imaging marker of IDH1 mutant glioma response to temozolomide therapy

Hyperpolarized d-[1-13C]gluconolactone monitors TERT-induced elevation in pentose phosphate pathway flux in brain tumors in vivo

Imaging a tumor hallmark: hyperpolarized [U-13C, U-2H]-glucose and [1-13C]-alanine non-invasively monitor TERT expression in gliomas in vivo

Author:Pavithra Viswanath  Georgios Batsios  Anne Marie Gillespie  Peng Cao  Peder Larson  Russell Pieper  Sabrina Ronen  

Institution:University of California San Francisco  

Session Type:Digital Poster  

Session Live Q&A Date:Digital Poster (All Week)  

Topic:Hyperpolarization and Molecular Imaging  

Session Name:Hyperpolarization 2  

Program Number:3022  

Room Live Q&A Session:

Metabolic reprogramming associated with IDH1-targeted treatments in low-grade glioma cell models: a 1H and 13C MRS study