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Development of a DNP-MRI molecular probe for detecting dipeptidyl peptidase-4 activity in vivo based on the substrate recognition mechanism.

Author:Akihito Goto  Hiroyuki Yatabe  Norikazu Koyasu  Kazutoshi Yamamoto  Mural Krishna  Keita Saito  Yoichi Takakusagi  Yutaro Saito  Shinsuke Sando  

Session Type:Digital Poster  

Session Date:Tuesday, 07 May 2024  

Session Name:Molecular & Metabolic Imaging  

Program Number:3182  

Room Session:Exhibition Hall (Hall 403)  

Institution:National Institutes of Health  National Institutes of Quantum Science and Technology  The University of Tokyo  

In vivo detection and imaging of aminopeptidase activities related to renin-angiotensin system using newly designed hyperpolarized MR probes

Author:Hiroyuki Yatabe  Yutaro Saito  Yoichi Takakusagi  Keita Saito  Kazutoshi Yamamoto  Murali Krishna  Shinsuke Sando  

Session Type:Power Pitch  

Session Date:Monday, 06 May 2024  

Session Name:Pitch: Metabolic & Hyperpolarized MR  

Program Number:0213  

Room Session:Power Pitch Theatre 2  

Institution:National Institutes for Quantum Science and Technology  National Institutes of Health  The University of Tokyo  

A Newly Designed Hyperpolarized Aminopeptidase N Probe Sensitively Detects Early Therapeutic Responses Heterogeneously on Pancreatic Tumors

Author:Norikazu Koyasu  Hiroyuki Yatabe  Yoichi Takakusagi  Yutaro Saito  Shinske Sando  Murali C. Krishna  Kazutoshi Yamamoto  

Session Type:Oral  

Session Date:Tuesday, 07 May 2024  

Session Name:Cancer Biomarkers: Bench to Bedside  

Program Number:0552  

Room Session:Room 331-332  

Institution:National Institutes of Health  National Institutes for Quantum and Radiological Science and Technology  The University of Tokyo