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Hyperpolarized 13C MRSI detects immunomodulatory responses to dimethyl fumarate and fingolimod therapies in a model of multiple sclerosis

Author:Caroline Guglielmetti  Christian Cordano  Chloe Najac  Ari Green  Myriam Chaumeil  

Session Type:Oral  

Session Date:Monday, 05 June 2023  

Session Name:Imaging Inflammation Across Neurological Diseases  

Program Number:0024  

Room Session:714A/B  

Institution :C.J. Gorter Center for High Field MRI, Leiden University Medical Center  University of California San Francisco  

Hyperpolarized [1-13C]pyruvate detects neuronal metabolic impairment in glucose transporter and pyruvate kinase deficient mice

Author:Caroline Guglielmetti  Huihui Li  Yoshitaka Sei  Lydia Le Page  Lauren Schields  Brice Tiret  Xiao Gao  Iris Lo  Talya Dayton  Jeffrey Rathmell  Matthew Vander Heiden  Ken Nakamura  Myriam Chaumeil  

Session Type:Digital Poster  

Session Date:Wednesday, 07 June 2023  

Session Name:The Bench: Preclinical Studies Within the Brain  

Program Number:3923  

Room Session:Exhibition Halls D/E  

Institution :Gladstone Institutes  Massachusetts Institute of Technology  University of California San Francisco  Vanderbilt Center for Immunobiology  Dana-Farber Cancer Institute