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Direct detection of 2HG and glutamate production using hyperpolarized [1-¹³C-5-¹²C]-a-ketoglutarate in cell and in vivo glioma models

Author:DongHyun Hong Yaewon Kim Chandrasekhar Mushti Noriaki Minami Anne Marie Gillespie Pavithra Viswanath Rolf E. Swenson Daniel B. Vigneron Sabrina M. Ronen

Session Type:Digital Poster

Session Date:Monday, 09 May 2022

Topic:Module 7: Spectroscopy & Hyperpolarization

Session Name:Hyperpolarization

Program Number:1064

Room Session:Exhibition Hall:S8 & S9

Institution:NHLBI University of California, San Francisco

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Proton and hyperpolarized ¹³C MRS based biomarkers response to the BAY-1436032 IDH inhibitor in cell and in vivo glioma models

Author:DongHyun Hong Marina Radoul Noriaki Minami Anne Marie Gillespie Russell O. Pieper Joseph Costello Pavithra Viswanath Sabrina M. Ronen

Session Type:Oral

Session Date:Thursday, 12 May 2022

Topic:Module 13: Preclinical Imaging

Session Name:Preclinical Cancer

Program Number:0677

Room Session:ICC Capital Suite 14-16

Institution:University of California, San Francisco

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