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Paramagnetic Rim Lesions in MS are characterized by heterogeneous damage and inflammatory activity: a combined T1 relaxometry-diffusion study

Author:Muhamed Barakovic  Riccardo Galbusera  Reza Rahmanzadeh  Matthias Weigel  Po-Jui Lu  Erik Bahn  Simona Schiavi  Alessandro Daducci  Pascal Sati  Pietro Maggi  Ludwig Kappos  Jens Kuhle  Laura Gaetano  Stefano Magon  Cristina Granziera  

Session Type:Digital Poster  

Session Date:Wednesday, 19 May 2021  

Topic:Multiple Sclerosis  

Session Name:MS: Myelin & Lesion Characterization  

Program Number:2810  

Room Session:Concurrent 6  

Institution:F. Hoffmann-La Roche Ltd.  Lausanne University Hospital  National Institute of Neurological Disorders and Stroke  Roche Innovation Center Basel F. Hoffmann-La Roche Ltd.  University Hospital Basel and University of Basel  University Medical Center  University of Verona  Cedars-Sinai Medical Center  Université catholique de Louvain  

Quantitative myelin-sensitive MRIs exhibit differential sensitivity to multiple sclerosis pathology in distinct brain lesions and regions

Author:Reza Rahmanzadeh  Po-Jui Lu  Muhamed Barakovic  Matthias Weigel  Laura Gaetano  Riccardo Galbusera  Thanh D. Nguyen  Francesco La Rosa  Daniel S. Reich  Pascal Sati  Yi Wang  Meritxell Bach Cuadra  Ernst-Wilhelm Radue  Jens Kuhle  Ludwig Kappos  Stefano Magon  Cristina Granziera  

Session Type:Digital Poster  

Session Date:Monday, 17 May 2021  

Topic:Novel & Multicontrast Approaches  

Session Name:Multicontrast Methods  

Program Number:1232  

Room Session:Concurrent 4  

Institution:Department of Radiology, Weill Cornell Medical College  Hoffmann-La Roche Ltd.  Neurologic Clinic and Policlinic, Departments of Medicine, Clinical Research and Biomedical Engineering, University Hospital Basel and University of Basel  Pharmaceutical Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd.  Radiology Department, Center for Biomedical Imaging (CIBM), Lausanne University and University Hospital  Research Center for Clinical Neuroimmunology and Neuroscience (RC2NB) Basel, University Hospital Basel and University of Basel  Signal Processing Laboratory (LTS5), Ecole Polytechnique Fédérale de Lausanne (EPFL)  Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, NIH, 10 Center Drive MSC 1400, Building 10 Room 5C103  Department of Neurology, Cedars-Sinai Medical Center  Translational Imaging in Neurology (ThINk) Basel, Department of Biomedical Engineering, University Hospital Basel and University of Basel