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Dynamic Contrast Enhanced and Diffusion MRI Show Rapid and Dramatic Changes in Tumor Microenvironment in Response to Inhibition of HIF-1a Using PX-478

Author:Benedicte F. Jordan  Matthew Runquist  Natarajan Raghunand  Ian Robey  Christine Howison  Amanda Baker  Ryan Williams  Lynn Kirkpartick  Garth Powis  Robert J. Gillies  

Session:Future MR Methods for Experimental Tumor Models  

Metabolite Changes in HT-29 Xenograft Tumors Following HIF-1a Inhibition with PX-478 as Studied by MR Spectroscopy in Vivo and Ex Vivo.

Author:Kvar Carl Lee Black  Benedicte F. Jordan  Ian F. Robey  Matthew Runquist  Garth Powis  Robert J. Gillies  

Session:MR in the Assessment of Cancer Therapy Models