Aritrick Chatterjee1
1Department of Radiology, University of Chicago, Chicago, IL, United States
Synopsis
Keywords: Body: Pelvis, Contrast mechanisms: Microstructure, Image acquisition: Quantification
Diffusion MRI is a key component of prostate MRI. A minimum of 2 b-values are needed to derive ADC map. PIRADS guidelines recommend a minimum of 3 b-values: low (0-100 sec/mm
2), intermediate (800-1000 sec/m
2) and high b-value (≥1400 sec/m
2, either acquired or calculated). The talk will highlight how the choice of b-values can significantly affect ADC estimates.
Additionally, we will look at recent advancements in quantitative MRI techniques that probe prostate tissue microstructure. We will look at imaging parameters used and results from these techniques: VERDICT, Restriction spectrum imaging, Hybrid Multi-dimensional MRI, time-dependent diffusion imaging, diffusion-relaxation correlation spectrum imaging, etc.
Overview of the talk
Diffusion MRI is a key component of prostate MRI. A minimum of 2 b-values are needed to derive ADC map. PIRADS guidelines recommend a minimum of 3 b-values: low (0-100 sec/mm2), intermediate (800-1000 sec/m2) and high b-value (≥1400 sec/m2, either acquired or calculated). The talk will highlight clinical DWI, PIRADS guidelines on acquisition, how the choice of b-values can significantly affect ADC estimates and prostate cancer diagnosis. We will discuss how the choice of b-value reveals different properties (perfusion/IVIM at low b, kurtosis at high b), signal contribution from different prostatic tissue components at different b-values, and effect of other imaging imaging on ADC and DWI.
Additionally, we will look at recent advancements in quantitative MRI techniques that probe prostate tissue microstructure. We will look at imaging parameters used and results from these techniques: VERDICT, Restriction spectrum imaging, Hybrid Multi-dimensional MRI, time-dependent diffusion imaging, diffusion-relaxation correlation spectrum imaging, etc. We will look at how these techniques leverage different imaging parameters, especially b-values to reveal distinct features.Acknowledgements
No acknowledgement found.References
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