Functional MRS: Neurotransmitters & Brain Metabolism
Francesca Branzoli1
1Paris Brain Institute - ICM, Sorbonne University, Inserm, Paris, France

Synopsis

Keywords: Contrast mechanisms: Spectroscopy, Neuro: Brain function

Functional MRS (fMRS) aims to measure, noninvasively, subtle changes in metabolic concentrations upon neural activation induced by sensory or cognitive tasks. fMRS may provide insights onto energy metabolism and brain function that are not captured by functional MRI, which is based on the blood-oxygenation level dependent effect. In this presentation, I will provide an overview of the metabolic changes that have been detected during neuronal activity and will discuss how these findings contributed to our knowledge of brain energy metabolism and neurotransmission. FMRS technical challenges and limitations will also be reviewed.

Functional MRS (fMRS) aims to measure, noninvasively, subtle changes in metabolic concentrations upon neural activation induced by sensory or cognitive tasks. fMRS may provide insights onto energy metabolism and brain function that are not captured by functional MRI, which is based on the blood-oxygenation level dependent effect. In this presentation, I will provide an overview of the metabolic changes that have been detected during neuronal activity and will discuss how these findings contributed to our knowledge of brain energy metabolism and neurotransmission. FMRS technical challenges and limitations will also be reviewed.

Acknowledgements

No acknowledgement found.

References

No reference found.
Proc. Intl. Soc. Mag. Reson. Med. 32 (2024)