Kartiga Selvaganesan1, Molly Sadinski1, Muller Gomes1, Aleksandar Nacev1, and Scott King1
1Promaxo Inc., Oakland, CA, United States
Synopsis
Keywords: Low-Field MRI, Low-Field MRI
Motivation: Access to MRI worldwide could be improved by reducing cost and increasing portability of the system. This requires imaging to occur in unshielded rooms making them highly susceptible to environmental noise; therefore, low-cost alternatives are needed for noise mitigation
Goal(s): Here we have designed a self-shielded RF coil array, made of resonating coaxial cables, for low-field parallel imaging in unshielded environments.
Approach: The proposed coils were tested against copper loops through phantom and clinical studies in various noise environments.
Results: The results indicate the self-shield coils are robust to external noise and produce images with sufficient signal and contrast to distinguish anatomical features.
Impact: With the
increased interest in the community towards developing accessible MR systems, the
proposed coil design presents a low-cost and resource efficient method for
noise mitigation, thereby allowing MRI to be portable and available to provide
point-of-care screening.
Introduction
Portable
MRI systems can significantly reduce the cost of and increase access to MR
scanners1,2. Such systems require imaging to take place outside
of Faraday shielded rooms resulting in increased electromagnetic interference
(EMI) and reduced image SNR. Promaxo’s low-field MR system, intended for in-office,
image guided prostate biopsies is especially prone to EMI arising from nearby
electrical equipment or radiation near the Larmor frequency. Current passive approaches
to shielding include applying conductive shielding close to the scanner, or
encompassing the body of the patient with a mesh cloth3. However, these techniques limit patient
access which is crucial for interventional procedures. A viable alternative is
using self-shield resonators or coaxial coils which have been shown to be
largely immune to EMI while still providing useful signal information4-6. In this study, we translate self-shielded coils to a
low-field environment (60-66mT) for imaging in a single-sided system, and
demonstrate the feasibility of using such coils to image in unshielded environments.
Methods
The
ability of the self-shielded coil to suppress EMI was evaluated with phantom
experiments using the single channel receive (Rx)-only surface coil shown in
Figure 1A. The coil consists of two-loops in a figure eight arrangement, where
each loop has a diameter of 7.5cm; a small gap was placed away from the tuning
and matching circuitry. The coil was tuned to 2.65MHz, with a bandwidth (BW)=20kHz,
and Q-factor=50.4. The performance of the self-shielded coil was evaluated
against a more conventional copper loop with similar dimensions (Figure 1B).
This coil was tuned to 2.65MHz, with BW=20kHz, and Q-factor=152.6.
Experiments
were conducted on Promaxo’s single-sided low-field MRI system (Figure 2A). The
experimental setup and phantom imaged are shown in Figure 2B. Each surface coil
was placed on top of an American College of Radiology approved extremity phantom
(ACR), positioned in the center of the imaging field of view (FOV). The noise
immunity of the coils was tested by introducing external noise signals at frequencies
of 2.65MHz, 2.66MHz, and 2.63MHz during signal acquisition. A 3-axis EMI
detector probe tuned to 2.65MHz was placed adjacent to the magnet and was used
to detect EMI simultaneous to MR signal acquisition. The 5-channel Rx-only coil
array shown in Figure 2C was used to test the clinical imaging performance of
the self-shielded coils. All images were acquired using a T2-weighted pulse
sequence with blipped RARE phase encoding, TE=5.2ms, TR=1.45s, echo train
length=12, and FOV=18cmx18cmx10cm.Results
Signal
collected from the single channel self-shielded and copper loop coils were
reconstructed with and without EMI cancellation for each experimental condition
(Figure 3). EMI cancellation was applied retrospectively by assuming a linear
convolution model between the EMI in the MR signal and the signal in the noise
detectors. The resulting noise estimates were then removed from the primary MR
signal. SNR – calculated by taking the mean of the signal amplitude in the phantom
region and dividing it by the standard deviation of the noise in the background
region – is reported in the bottom right corner of each image.
Figure 4
shows prostate images of a human subject obtained using a 5-channel Rx-only,
self-shieled RF array coil. Four slices are shown from a 3D volumetric imaging
study with an in-plane resolution of 1.5mm x1.5mm. Arrows point to the rectum
and prostate anatomy.Discussion
We have
designed and implemented a self-shielded RF coil that allows for low-field MR
imaging in unshielded environments.
The
phantom imaging experiments show that noise suppression of the self-shielded RF
coil is much higher than that of a conventional copper loop of similar
dimensions. In the case of the copper loop, while EMI cancellation through
signal postprocessing was able to remove a significant amount the background
noise it is still difficult to delineate phantom features. Moreover, the image
quality is not as high as those obtained using the self-shielded loop. Quantitative
comparison of image SNR asserts a similar trend. EMI cancellation of signal
acquired with the self-shielded coil has little, if any, improvement on image SNR,
and the coil appears to be tolerant to external signals are various
frequencies.
Clinical imaging
experiments demonstrate proof-of-concept that RF arrays built from self-shield loops
can be used for parallel imaging at low-field and generate images that have
sufficient SNR to visualize key anatomical features.Conclusion
In
conclusion, the proposed self-shielded coil design provides SNR robustness to
external noise and promising image quality. Such coils can allow for MR imaging
to take place in unshielded rooms, increasing the portability of MRI, thereby making
it accessible to provide point-of-care screening.Acknowledgements
No acknowledgement found.References
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