Nitin Jain1, Rajdeep Das1, Harsh Agarwal1, Sajith Rajamani1, and Ramesh Venkatesan1
1GE HealthCare, Bangalore, India
Synopsis
Keywords: Low-Field MRI, Data Acquisition, PROPELLER, Image Reconstruction, Compressed Sensing, NUFFT, Acceleration
Motivation: Mid-field MRI have lower SNR so data acquisition is associated with longer data acquisition time. Therefore, develop fast imaging technique with motion robust data acquisition with minimal SNR penalty due to fast imaging.
Goal(s): Develop a robust image reconstruction technique for compressed sensing (CS) accelerated PROPELLER acquisitions.
Approach: A new iterative reconstruction technique based on NUFTT and CS for PROPELLER acquisitions.
Results: MRI imaging of ISMRM-NIST phantom and volunteer scan were acquired and reconstructed with minimal under-sampling artifacts such as haze and streaks with PROPELLER acceleration.
Impact: Compressed sense
accelerated PROPELLER can acquire high quality motion robust MRI images at
mid-field MRI. Proposed MR image reconstruction technique for compressed
sensing accelerated PROPELLER technique can
enable acquisitions requiring longer scan time due to SNR.
INTRODUCTION
Periodically rotated
overlapping parallel lines with enhanced reconstruction (PROPELLER) acquisition
technique has been proven to be quite effective in reduction of motion
artifacts [1] and B0 inhomogeneities. This acquisition involves data collection
over rectangular strips, called blades, rotated about k-space origin. As a
certain portion of the central k-space region is sampled in each blade, it
makes propeller acquisition slower as compared to conventional FSE
acquisitions. A blade dropping approach has been proposed elsewhere [2].
In this manuscript, a PROPELLER acquisition can be
accelerated by partially acquiring views in each blade. This type of acquisition is done using 1D
random sampling mask scheme with denser sampling near the center of the blade k-space.
Each blade is acquired either with same or different sampling view mask as
shown in Figure 1(a). It was demonstrated that, when compared with fully sampled
PROPELLER, a combination of the proposed under-sampling pattern and iterative
NUFFT [3] based CS [4] reconstruction reduces imaging time and produces images
with negligible aliasing artifacts, haze and without any additional significant
increase in the noise. METHOD
Fast MR Image
Reconstruction:
The proposed MR image reconstruction consist of two steps. First at the blade
level each subsampled blade is inverse Fourier transformed from k-space to
image-space using NUFFT [4] and phase correction is done to make sure that the
point of rotation is at the center of k-space. The phase corrected image-space
blade is then Fourier transformed to k-space to give phase corrected subsampled
k-space. Second, an iterative conjugate gradient optimization method is used to
combine the phase corrected blade k-space into final reconstructed image. Phase
corrected blade k-space is used as ground truth data and L1 norm is used for
regularization in iterative conjugate gradient method. Voronoi based density
correction factor [5] is used to accelerate convergence of the iterative NUFFT
image estimate. The flow diagram for reconstruction chain is shown in Figure
1(b).
Data Acquisition:
Data was acquired using a research 0.5T MR system which is obtained by ramping
down commercial GE 1.5T MRI to 0.5T and modified transmit and receive RF chain.
A health volunteer was scanned in an institutions IRB approved study with
signed informed consent. Scanner software was modified to acquire fully sampled
and prospectively subsampled Diffusion NIST phantom and a healthy volunteer. Number
of phase encoding lined in the blade were reduced by factor of R as compared to
fully sampled blade using variable density compressed sensing sampling. Number
of blades in fully sampled and prospectively subsampled acquisition could be
different as number of acquired views in each blade has to be the multiple of
echo train length. RESULT
Figure 2 shows phantom images with
unaccelerated and accelerated proposed fast image reconstruction technique
reconstructed MRI image. The proposed fast image reconstruction technique is
used to reconstruct prospectively subsampled PROPELLER acquisition with acceleration
factors of 2.0 and 3.0. The view subsampling mask is same across all the blades
for this acquisition. Figure 3 shows Axial T2w MRI of brain
with unaccelerated and accelerated (R=2.0) fast MRI image reconstruction. The
accelerated data acquisition is done for same view mask across blades and
different view mask across the blades. DISCUSSION AND CONCLUSION
Fast MR image reconstruction technique
proposed in this abstract successfully reconstructed blade level compressed
sensing subsampled PROPELLER acquisition. Un-sampling artifacts such as haze
and streaks were not visible in the reconstructed MRI images. Same and
different sub-sampling mask for each blade was compared and shown similar
qualitative performance.
Accelerated PROPELLER MRI at 0.5T is
essential to acquire motion robust high SNR MR image reconstruction during long
acquisition times. Compared to parallel imaging, center of k-space is fully
sampled in compressed sensing so compressed-sensing is more SNR efficient
sampling pattern. Successful accelerated phantom and volunteer images acquired
at 0.5T with proposed fast MR image reconstruction technique shows feasibility
of longer higher resolution motion robust data acquisition at 0.5T.Acknowledgements
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