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FRACTURE compared to CT for detecting structural lesions of the sacroiliac joint in axial spondyloarthritis1the first affiliated hospital of nanjing medical university, nanjing, China, 2Philips healthcare，shanghai， China, shanghai, China, 3nanjing medical university, nanjing, China
Synopsis
Keywords: Other Musculoskeletal, MSK
Motivation: The detection of structural damage of the sacroiliac joint is essential for diagnosing axial spondyloarthritis.
Goal(s): To assess the diagnostic performance of FRACTURE sequence in detecting structure lesions compared to CT.
Approach: A retrospective study was conducted on 83 patients with definite axial SpA who underwent MRI and CT scans of the sacroiliac joint between 2021 and 2022. An overall impression of sacroiliitis grade was also provided according to the scoring system of the modified New York criteria.
Results: When compared to CT as the standard, FRACTURE demonstrated high agreement with AUC values of 0.908, 0.943, 0.918 and 0.944 for sacroiliitis grade.
Impact: FRACTURE can evaluate structural lesions and demonstrate good diagnostic performance in patients with SpA.
Background
The detection of structural damage, such as erosions, sclerosis, and ankyloses, of the sacroiliac joint (SIJ) is essential for diagnosing axial spondyloarthritis (axSpA). However, CT is considered more effective than conventional MRI in assessing structural lesions.Purpose
To assess the diagnostic performance of FRACTURE (fast field echo resembling a CT using restricted echo-spacing) sequence in detecting structure lesions in axial spondyloarthritis (SpA) compared to T1W imaging and CT.Materials and Methods
A retrospective study was conducted on 83 patients with definite axial SpA who underwent MRI and CT scans of the sacroiliac (SI) joint between 2021 and 2022. The FRACTURE and TIWI sequence of MRI and CT scan of the SIJ were available at the same time. The image of SIJ were scored for structural lesions, including joint space changes (score 0–5), subchondral erosions (score 0–3) and subchondral sclerosis (score 0–2). An overall impression of sacroiliitis grade was also provided according to the scoring system of the modified New York criteria.Results
A total of 166 SIJ (83 participants) were available for analysis. When compared to CT as the standard, FRACTURE demonstrated high agreement with AUC values of 0.908, 0.943, 0.918 and 0.944 for joint space changes, subchondral erosions, subchondral sclerosis, and overall impression of sacroiliitis grade. FRACTURE had a higher diagnostic accuracy than T1WI for joint space changes (91.8% vs 70.5%), subchondral erosion (93.3% vs 56.4%), subchondral sclerosis (94% vs 77.6%), and overall impression of sacroiliitis grade (98.9% vs 75.3%).Conclusion
FRACTURE imaging can evaluate structural lesions and demonstrate good diagnostic performance in patients with SpA.Acknowledgements
I would like to give my heartfelt thanks to all the people who have ever helped me in this paper.References
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