Runyu Yang1, Haozhong Sun1, Haokun Li1, and Huijun Chen1
1Center for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University, Beijing, China
Synopsis
Keywords: Image Reconstruction, Heart, Reconstruction
Motivation: Try to obtaining high spatial and temporal resolution image in dynamic MRI.
Goal(s): The plug and play truncated low rank optimization combined iterative soft thresholding(PNPT-) embedded method was proposed to reconstructe data and tested to accurately estimate the rank function for dMRI reconstruction.
Approach: The PNPT- method uses truncated nuclear norm combined iterative soft thresholding to assign different shrink values to different singular vectors, enabling the preservation of essential image information while effectively eliminating noise.
Results: The embedded method was proposed to reconstructe data and tested to accurately estimate the rank function for dMRI reconstruction.
Impact: The proposed method demonstrated reduced
aliasing artifacts compared to other methods and yielded better reconstruction
images in cine and perfusion data. Consequently, it provided more
accurate and efficient image information, benefiting the clinical diagnosis of
heart-related diseases.
Introduction
Dynamic
magnetic resonance imaging (dMRI) plays an important role in clinical applications
[1]. Nevertheless, achieving high spatial and temporal resolution images in
dynamic MRI poses a significant challenge due to the constraints imposed by the
Nyquist criterion [2,3]. One primary approach involves under-sampling the raw
data acquisition and utilizing advanced reconstruction techniques to enhance the quality of the image,
such as kt-SLR[4] and L+S [5]. However, both approaches encounter imprecise challenges in solving
singular values with low rank constraints, potentially resulting in inaccurate
suboptimal outcomes. Truncated nuclear norm [6,7] to assign different shrink
values to different singular vectors, enabling the preservation of essential
image information while effectively eliminating noise. It can be embedded into
various reconstruction methods using low rank constraints. Iterative Soft Thresholding (IST)
algorithm [5]
exhibits a reduced parameter count and superior solving efficiency. Hence, the plug and play truncated low rank optimization combined iterative
soft thresholding (PNPT-) embedded method was proposed to reconstructed
data and tested to accurately estimate the rank function for dMRI
reconstruction.
Method
Theory: Generally, the discretization form of the dynamic MRI
method can be presented as:$$d = E\left( X \right) + n \tag{1}$$ where $$$X \in {\mathbb{C}^{{N_x}{N_y} \times {N_t}}}$$$ denotes the image series that expands along the time
dimension,$$$\mathbb{C}$$$ denotes
the complex set, $$${N_x},{N_y}$$$ and $$${N_t}$$$ denote
the width, height and the total time frames, respectively;$$$d$$$ denotes
the stacked $$$\left( {{\mathbf{k}},t} \right)$$$ space acquired
data vector;$$$E$$$ denotes
the MRI encoding operator modeling the under-sampling mask, Fast Fourier
Transform (FFT) and coil sensitivity,$$$n$$$ denotes
the noise.Since
the $$$X$$$
in dMRI usually can be assumed to have a
low-rank structure [4,5] ,
given $$$l = \min \left( {{N_x} \times {N_y},{N_t}} \right)$$$.the
rank’s truncated parameter $$$t$$$.The truncated nuclear norm is
defined as follows:$${\left\| {{X}} \right\|_{t,*}} = \mathop \sum \limits_{i = t + 1}^l {\sigma _i}\left( X \right) \tag{2} $$where $$${\sigma _i}\left( \cdot \right)$$$ is the $$$i$$$th largest eigenvalue of $$$X$$$. To
solve the truncated nuclear norm minimization problem, the von Neumann’s lemma [8-10] were
used. And Iterative Soft Thresholding
(IST) algorithm is used in combination to improve the solving efficiency.The truncated
nuclear norm can be
embedded into kt-SLR and L+S methods. Therefore, PNPT-SLR and PNPT-L+S method can be obtained
as follows respectively:$$\mathop {\min }\limits_X {\left\| X \right\|_{t,*}} + {\mu _x}{\left\| {TX} \right\|_1}\;{\rm{s}}.{\rm{t}}.\;E\left( X \right) = d\tag{3}$$ $$\mathop {\min }\limits_{L,S} {\left\| L \right\|_{t,*}} + {\mu _S}{\left\| {TS} \right\|_1}\;{\rm{s}}.{\rm{t}}.\;X = L + S,E\left( {L + S} \right) = d\tag{4}$$where $$${\mu _x}$$$ and $$${\mu _s}$$$ are constraint operators.
Retrospective experiments: A
cardiac cine dataset (CineSet) [11] and a perfusion dataset (PerfusionSet) [4,12] acquired with three simulated undersampling factors (R) of 2, 4 and 6, were used to verify the method. The CineSet contains cardiac cine MR images of randomly selected 8
cases from the OCMR dataset [11]. The PerfusionSet contains 2 public cardiac
perfusion MR data from [4] and [12].The
Cartesian masks with varying sampling ratios [13] were used in experiments.Reconstruction performance was
evaluated using the Peak Signal to Noise Ratio (PSNR) and Root Mean Squared
Error (RMSE) .The
regions of interest (ROI) for the blood pool and myocardium in perfusion data were
manually sketched.Results
Firstly,
the proposed embedded methods consistently attained the highest PSNR and the
lowest RMSE as shown in Table 1. In Figure 2, the
reconstructed images obtained from kt-SLR reveal noticeable noise in spatial
domain, contrasting with the PNPT-SLR that exhibits significantly reduced noise
levels in the corresponding images as shown by the red arrows. L+S offers a
smoother image, whereas PNPT-L+S renders the heart's mitral valve more
distinctly as shown by the white arrows. In general, the proposed embedded
methods have smaller errors in both spatial and temporal dimensions. From
Figure. 3, the images reconstructed by kt-SLR and L+S methods had strong
blurring artifacts, especially in the boundary area of the interventricular
septum due to inaccuracy utilization of the low-rank prior. In contrast, the
proposed embedding method effectively highlighted the boundary of the
interventricular septum over time as shown by the red
arrows, surpassing the performance of the other methods. Due to improve the
low rank constraints, the proposed method can more accurately depict the
intensity change of contrast agent over time as show in Figure. 4. Notably, as
the contrast agent concentration increased, the curve derived from the proposed
method closely matched the ground truth and exhibited fewer fluctuations
compared to other methods.Conclusions
The
plug and play truncated low rank optimization combined iterative soft
thresholding embedded method was proposed to reconstruct data. The proposed model
has an improved approximation effect for low-rank prior.References
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