Rubén Bosch1,2, José Miguel Algarín1,2, Teresa Guallart-Naval1,2, Francisco Juan-Lloris3, Jesús Conejero1,2, and Joseba Alonso1,2
1i3M, CSIC, Valencia, Spain, 2Universitat Politècnica de València, Valencia, Spain, 3Physio MRI SL, Valencia, Spain
Synopsis
Keywords: Data Acquisition, Software Tools, Radiofrequency, MaRCoS, open-source
Motivation: MaRCoS is an open-source tool integrating hardware, firmware, and software for low-field MRI system control. But releases lacked user-friendly features, requiring technicians to handle automatable operations manually.
Goal(s): To simplify clinical workflows, we developed a device for RF coil impedance tuning and matching in systems controlled by MaRCoS.
Approach: Our approach involved designing a TM device using switchable capacitors and testing it in a real clinical environment on a portable 72 mT system.
Results: The auto-TM system, tested on 20 volunteers (40 protocols), significantly accelerated and improved workflow compared to manual methods, marking a substantial advancement in MRI system efficiency and usability.
Impact: The introduction of our automatic tuning and matching device eases low-field MRI systems controlled by MaRCoS. By simplifying clinical workflows and improving efficiency, this innovation enhances the user experience, simplifing the workflow under clinical environments.
Introduction
MaRCoS is
constituted by an interplay of open-source hardware, firmware, and software
components for MRI control, featuring high-performance at a low-cost. While
previous efforts have predominantly concentrated on enhancing system
reliability, the user experience in operating MaRCoS has often been
disregarded.
One example
is the required manual impedance tuning and matching (TM) calibration of the RF
coil to the Larmor frequency. Manual TM is time-consuming and hardly
reproducible, and thus an obstacle to smooth clinical practice. To address this
challenge, we introduce an automatic 50 Ohm TM device (Figure 1) for low
frequencies, aiming to streamline the user experience and ensure straightforward
operation in diverse clinical environments.Methods
We designed
an auto-TM system (Figure 1.a) based on relays that add or remove capacitors
from the RF circuitry, with a total of 8192 potential combinations for
impedance optimization [1]. The device is commanded by an Arduino
microcontroller that switches the relays based on impedance measurements with an
open-source NanoVNA [2]. The system has been conceived for frequencies around 3
MHz but can be trivially extrapolated to other frequencies.
A critical
aspect is to prevent noise from reaching the RF chain due to the auto-TM
system. We have done this by boxing the system inside a Faraday shield (Fig.
1a) and placing all wires in grounded shields.
In parallel
with the hardware development, we upgraded the MaRCoS graphical user interface
[3] to incorporate the automatic tuning process into the scanner autocalibration
procedure (Figure 1.b). This integration ensured a user-friendly experience,
allowing operators to initiate the auto-TM seamlessly within the interface of
the MaRCoS system.
To assess
the effect of our auto-TM device and its influence on user experience, we
conducted extensive in vivo tests. This evaluation took place within a portable
and cost-effective 72 mT MRI scanner [4], installed in a major hospital. The
same protocol, involving full system autocalibration and four RARE sequences
with different parameters, was conducted on both knees of a total of 50
volunteers (20 of them with the auto-TM), and we compared automatic against
manual TM in terms of usability and image quality.Results
Executing
the full protocol with our automatic tuning device was straightforward,
requiring only a few clicks within the MaRCoS interface. This simplified
process streamlined the workflow for all participants, eliminating the
complexities associated with manual TM and ensuring efficient protocol
execution.
Figure 2.a
shows noise measurements (top) and its corresponding spectrum (bottom) obtained
from automatic and manual TM in two distinct volunteers. Both measurements show
clean profiles without any relevant electromagnetic interferences, with a
similar value for root mean square noise voltage. This indicates the level of additional
noise introduced by our automated system can be made negligible under real
conditions.
Figures 2.b
and 2.c present images acquired using manual (b) and automatic (c) tuning
matching from the same volunteers featured in Figure 2.a. The quality of both
images is comparable.Discussion
Automatic TM
eases adjustments to the RF coil impedance and eliminates the need for
time-intensive manual calibrations. In this way, we have significantly enhanced
the efficiency of the TM process, improving the way RF coil impedance is
managed in our MRI system and enabling non-experts to carry out the procedure
with minimal training.
These
findings reinforce the efficacy and reliability of our automatic tuning device,
demonstrating its ability to produce images of comparable quality to those
generated through tedious manual tuning processes. These consistent results
further validate the seamless integration of our technology into the MRI
workflow, improving user experience in clinical environments.Conclusion
In
conclusion, our study introduces a new tool for MRI system operation through
the integration of an automatic tuning and matching device within the open MaRCoS
ecosystem. By addressing the limitations of manual RF coil tuning and matching,
our solution streamlines the workflow, enhancing operational efficiency and
user experience. The execution of protocols requires only a few clicks. After
imaging 50 volunteers (100 limbs) under real clinical conditions, we conclude
the auto-TM is a valuable upgrade, easy to install, seamlessly integrated,
simple to use, and with direct impact on clinical practice, thereby
establishing new standards inside MaRCoS.Acknowledgements
Project
funded by: the EU (EIC Transition, 101136407), EURAMET (22HLT02), Spanish
MICINN (PID2022-142719OB-C22), the Valencian Government (CIPROM/2021/003) and
the Valencian Innovation Agency (INNVA1/2022/4, INNVA1/2023/30).References
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S. M., DelaBarre, L., Gopinath, A., & Vaughan, J. T. (2015). Design of an
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[2] https://nanovna.com/
[3] https://github.com/yvives/PhysioMRI_GUI
[4] Guallart-Naval,
T., Algarín, J. M., Pellicer-Guridi, R., Galve, F., Vives-Gilabert, Y., Bosch,
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Borreguero, J., Marcos-Perucho, A., Negnevitsky, V., Martí-Bonmatí, L., Ríos,
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https://doi.org/10.1038/s41598-022-17472-w