Synopsis

Keywords: Body: Kidney, Contrast mechanisms: Microstructure, Contrast mechanisms: Perfusion

Renal function and pathology in a wide variety of contexts (healthy filtration, chronic kidney disease, allograft function) can be sensitized and monitored with the wide armamentarium of tools provided by quantitative MRI. These measures probe microstructure (DWI, elastography), microcirculation/hemodynamics (ASL, DCE, PC-MRI), and oxygenation (BOLD), among others. For each of these approaches there have developed both translational efforts of harmonization (to generate standardizable variants to escalate multi-site evidence generation and incorporation into clinical trials), and innovation (to explore and validate each MR contrast and its relationship to tissue function). This talk will briefly summarize these two branches of work.