Synopsis

Keywords: Body: Liver, Cross-organ: Obesity, Cross-organ: Metabolic disease

Organ-Specific Fat Quantification: Liver and Pancreas

Hepatic steatosis is the abnormal accumulation of triglycerides in the hepatocytes whereas a fatty pancreas is the abnormal pancreatic fat accumulation. Both are shown to be associated with metabolic syndrome, Type 2 diabetes, and cardiovascular diseases. The main approach to quantifying liver and pancreas fat is chemical shift magnetic resonance imaging (MRI) techniques. MRI-proton density fat fraction (MRI-PDFF) is shown to be an excellent diagnostic value for the assessment of hepatic fat content and classification of histologic steatosis grades in non-alcoholic fatty liver disease.