Synopsis

Keywords: Body: Respiratory, Contrast mechanisms: Hyperpolarization, Contrast mechanisms: fMRI

We will explore new fundings using pulmonary functional MRI using inhaled 129Xe gas that help explain long-COVID in patients.

Over the past two-years, post-acute COVID-19 sequelae have been defined and redefined for people with so-called Long-COVID. Post-acute COVID-19 syndrome (PACS) is the umbrella term that describes continuing or new symptoms which persist four weeks or more after an acute COVID-19 infection, including respiratory, neurological and psychological symptoms. While a majority of previously hospitalized people with PACS have reported improved pulmonary function and exercise capacity 12-months after infection, at least one persistent symptom has also been reported in 41-85% patients with PACS. Chest CT is nearly universally available and the clinical-mainstay for the evaluation of pulmonary abnormalities resultant from COVID-19 infection and in people with PACS (10). In this educational session, we will summarize and explore the role of pulmonary functional MRI using inhaled 129Xe gas and the results of studies in the UK, China and North America in people complaining of symptoms, many weeks post-infection.

Acknowledgements

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References

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