Keywords: Cardiovascular: Vascular
Intracranial aneurysm is a major cause of hemorrhagic stroke. Traditional imaging methods only evaluate the lumen geometry but not the underlying pathology of the aneurysm wall. Contrast enhanced vessel wall MRI can identify the neovasculature – a marker of inflammation. Dynamic contrast enhanced MRI can identify wall permeability. 4D flow MRI can identify hemodynamic factors that contribute to aneurysm progression and rupture. These MRI-based novel imaging markers have been investigated in many cross-sectional and longitudinal clinical studies and showed promises. This talk will cover both the recent technical development of intracranial aneurysm imaging and also its applications.1. Huibin Kang, De-Cai Tian, Xinjian Yang, Yisen Zhang, Binbin Sui, Mirzat Turhon, Mahmud Mossa-Basha, Michael R Levitt, David Hasan, and Chengcheng Zhu. A Randomized Controlled Trial of Statins to Reduce Inflammation in Unruptured Cerebral Aneurysms Journal of the American College of Cardiology: Cardiovascular Imaging, 2022 Sep;15(9):1668-1670.
2. Qichang Fu, Yuting Wang, Yi Zhang, Yong Zhang, Xinbin Guo, Haowen Xv, Zhiqiang Yao, Meng Wang, Michael Levitt, Mahmud Mossa-Basha, Jinxia Zhu, Jingliang Cheng, Sheng Guan, Chengcheng Zhu. Qualitative and Quantitative Wall Enhancement on Magnetic Resonance Imaging Is Associated With Symptoms of Unruptured Intracranial Aneurysms Stroke 2021 Jan;52(1):213-222.
3. Florent Gariel et al. Increased Wall Enhancement During Follow-Up as a Predictor of Subsequent Aneurysmal Growth. Stroke . 2020 Jun;51(6):1868-1872.