Keywords: Contrast mechanisms: Spectroscopy
Magnetic resonance spectroscopy (MRS) is a powerful, quantitative imaging technique to measure brain metabolites for characterizing neurological diseases. Its impact, however, is limited due to small sample sizes and methodological variability. The lack of standardization in data collection and processing makes it challenging to perform multisite studies that support widespread clinical MRS use. This talk will provide an overview of advanced applications of MRS and the technical and biological factors to consider when aggregating data for multisite trials. The goal is to provide novice and experienced technologists with the necessary knowledge for conducting MRS multisite studies.