Myelin Imaging in Preclinical Animal Models: Techniques & Applications
Ella Wilczynski1
1Department of Biomedical Engineering, Tel Aviv University, Tel Aviv, Israel
Synopsis
Keywords: Neuro: Brain, Neuro: White matter, : Preclinical/Animal
Preclinical studies are essential for understanding myelin-related
disorders, developing innovative methodologies, and comprehending their diverse
manifestations. In this talk, we will explore the reasons for conducting
preclinical experiments, discuss their advantages and disadvantages, and
outline key adaptations for transitioning between preclinical and clinical
sequences. Examples of histology validations, diverse animal models, and
disparities with the human context will be presented. Valuable tips for
researchers entering the field of myelin preclinical studies will also be
provided. Join us to gain valuable insights into the crucial role of
preclinical research in unraveling myelin pathologies.
Preclinical studies are essential for understanding myelin-related
disorders, developing innovative methodologies, and comprehending their diverse
manifestations. In this talk, we will explore the reasons for conducting
preclinical experiments, discuss their advantages and disadvantages, and
outline key adaptations for transitioning between preclinical and clinical
sequences. Examples of histology validations, diverse animal models, and
disparities with the human context will be presented. Valuable tips for
researchers entering the field of myelin preclinical studies will also be
provided. Join us to gain valuable insights into the crucial role of
preclinical research in unraveling myelin pathologies.Acknowledgements
No acknowledgement found.References
No reference found.
Proc. Intl. Soc. Mag. Reson. Med. 31 (2023)