Myelin Imaging in Preclinical Animal Models: Techniques & Applications
Ella Wilczynski1
1Department of Biomedical Engineering, Tel Aviv University, Tel Aviv, Israel

Synopsis

Keywords: Neuro: Brain, Neuro: White matter, : Preclinical/Animal

Preclinical studies are essential for understanding myelin-related disorders, developing innovative methodologies, and comprehending their diverse manifestations. In this talk, we will explore the reasons for conducting preclinical experiments, discuss their advantages and disadvantages, and outline key adaptations for transitioning between preclinical and clinical sequences. Examples of histology validations, diverse animal models, and disparities with the human context will be presented. Valuable tips for researchers entering the field of myelin preclinical studies will also be provided. Join us to gain valuable insights into the crucial role of preclinical research in unraveling myelin pathologies.

Preclinical studies are essential for understanding myelin-related disorders, developing innovative methodologies, and comprehending their diverse manifestations. In this talk, we will explore the reasons for conducting preclinical experiments, discuss their advantages and disadvantages, and outline key adaptations for transitioning between preclinical and clinical sequences. Examples of histology validations, diverse animal models, and disparities with the human context will be presented. Valuable tips for researchers entering the field of myelin preclinical studies will also be provided. Join us to gain valuable insights into the crucial role of preclinical research in unraveling myelin pathologies.

Acknowledgements

No acknowledgement found.

References

No reference found.
Proc. Intl. Soc. Mag. Reson. Med. 31 (2023)