Synopsis

Keywords: Contrast mechanisms: Perfusion, Neuro: Cerebrovascular, Image acquisition: Quantification

I will describe the acquisition and analysis of ASL data in order to produce accurate images of perfusion or blood flow, with a focus on the brain. I will describe recent advances in acquisition to improve SNR and pragmatic approaches to kinetic modelling of the signal for accurate and precise quantification. I will discuss the benefits of multi-time point measurements which allow correction for and estimation of arterial transit time.