Synopsis

Keywords: Neuro: Cerebrovascular, Contrast mechanisms: Diffusion, Image acquisition: Image processing

The brain waste clearance system plays a critical role in the removal of toxic substrates from the brain to maintain parenchymal homeostasis. Different pathways are hypothesized to explain this complex network of brain clearance. Regardless of the directionality, perivascular spaces are known to act as highways of influx and efflux, facilitating the glia-lymphatic drainage. In this educational talk, we will discuss brain clearance system and ways it can be assessed using neuroimaging techniques. We will then discuss if and how the clearance system may change in the presence of neuroinflammation.

Summary

The brain waste clearance system plays a critical role in the removal of toxic substrates from the brain to maintain parenchymal homeostasis. Different pathways are hypothesized to explain this complex network of brain clearance. Regardless of the directionality, perivascular spaces are known to act as highways of influx and efflux, facilitating the glia-lymphatic drainage. In this educational talk, we will discuss brain clearance system and ways it can be assessed using neuroimaging techniques. We will then discuss if and how the clearance system may change in the presence of neuroinflammation.

Acknowledgements

No acknowledgement found.

References

No reference found.