Studies with Single Subjects or Large Numbers of Volunteers - Why, & How?
Wietske van der Zwaag1
1Spinoza Centre for Neuroimaging, Netherlands

Synopsis

Keywords: Neuro: Brain function, Neuro: Brain, Neuro: Brain connectivity

In the functional MRI field, datasets continue to grow. Interestingly, there are two different trends: There are currently multiple efforts towards collection of datasets with a huge number of participants, to capture the variance in a population, or to use the power of massive averaging to discover subtle brain function patterns. A second trend is towards exhaustive sampling of a single participant (or a few), arguing that measurements of one brain likely generalize to most other brains. Dense sampling allows experiments with either many conditions or extremely detailed images, exploring different types of variance. This talk will discuss both trends.

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Proc. Intl. Soc. Mag. Reson. Med. 31 (2023)