Synopsis

Keywords: Neuro: Brain, Contrast mechanisms: Electromagnetic Tissue Properties, Contrast mechanisms: Relaxometry

Traditional MWI relies on the observation of a short T2 component (Mackay et al., 1994), yet there are other ways in which myelin affects the observed MR signal: by affecting the longitudinal magnetization recovery thanks to magnetization and chemical exchange mechanisms and by changing the free induction decay of the visible signal due to the myelin diamagnetic properties. This talk will focus on three recently proposed methods that explore these properties: ViSTa (Oh et al Neuroimage, 2013), gradient echo based myelin water imaging (Nam et al, Neuroimage 2015) and multi-compartment relaxometry myelin water imaging (Chan et al, Neuroimage, 2020).