In-Vivo Spectroscopy
Risto Kauppinen1
1University of Bristol, Bristol, United Kingdom

Synopsis

Keywords: Cross-organ: Cancer

High field 3T MRI systems are now clinical routine in cancer management offering SNR and spectral resolution for in vivo 1H MRS. To obtain high-quality metabolite profiles from tumours in situ and to widen the profiles for cancer genetic markers, spectral localisation, acquisition, processing and peak assignments must be optimised and harmonised for 3T MRS. Metabolite profiles obtained by state-of-the art 1H MRS have proven to aid in pre-surgical grading of adult and paediatric brain, prostate and breast tumours. The lecture will focus on technical aspects of 1H MRS for clinical tumour evaluations.

Synopsis

High field 3T MRI systems are now clinical routine in cancer management offering SNR and spectral resolution for in vivo 1H MRS. To obtain high-quality metabolite profiles from tumours in situ and to widen the profiles for cancer genetic markers 1, spectral localisation, acquisition 2, processing and peak assignments 3 must be optimised and harmonised for 3T MRS. Metabolite profiles obtained by state-of-the art 1H MRS have proven to aid in pre-surgical grading of adult 4 and paediatric brain 5, prostate 6 and breast 7 tumours. The lecture will focus on technical aspects of 1H MRS for clinical tumour evaluations.

Acknowledgements

No acknowledgement found.

References

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Proc. Intl. Soc. Mag. Reson. Med. 31 (2023)