Rajesh Harsh1, Dharmesh Verma1, Aparna Gunvant Raut1, and Mahadev Kashinath Dipnaik1
1Medical Systems Division, S.A.M.E.E.R. Mumbai, Mumbai, India
Synopsis
Keywords: New Devices, Spectroscopy, System -on-chip,MIMO Based smart MRI Spectrometer
The
increasing complexity of modern MRI hardware design makes system challenging. MRI systems equipped with multi-channel
exciter and multi-channel data-acquisition modules, particularly
high-channel-counts often requires a huge cost. This abstract summaries
the design and development of a low cost, small form factor, system on chip approach
to realize a complete 1.5 T MRI
spectrometer on a small chip of 28 nanometer fabric. The developed system executes parallel image processing algorithms and compatible instrumentation for accurate spatial and temporal requirements.
Introduction
The demand for developing a complete
customized and reconfigurable embedded spectrometer for Magnetic Resonance
Imaging with power of on chip data acquisition, processing and image
reconstruction has been the need of the recent times [1]. This abstract
summaries succinctly the design and development of a successfully integrated
state of art but extremely powerful, ‘System on chip’, 1.5 T MRI spectrometer with a customized clinical user
interface to generate human anatomical pulse excitation systems of any shape,
of any width with very high precision time of nanoseconds accuracy. These
waveforms are developed for not only multi-slice applications of Larmor
frequency signals but also for gradient signals too. The power of parallel
computing with multi-thread on chip processor layers have been exploited to
develop some high speed On-chip image reconstruction algorithms of even sub
Nyquist model [2]. which saves huge time in clinical applications as compared
to the conventional available MRI systems. Field Programmable Gate Arrays
(FPGAs) are used by exploiting the reconfigurable resources and implementing the
complicated image processing algorithms at very
fast speeds in real time in parallel and pipelined fashion using HDL
languages for customized MRI spectrometer.Method
Speed of MR imaging is
primarily determined by the speed and time elapsed by the system to acquire,
process and generate the clinical image. In this approach, the accelerators with
desired computing core are interfaced directly to the programmable RTL logic layers.
[3][4]. This type of coupled togetherness of logic and processor layer
accelerators exposes no communication overhead and offers quick
synchronization, processing and transforms of data to spatial domain outputs
for evaluation to clinicians and medical fraternity. A 28 nanometer fabric
which include dual ARM cortex processors and programmable electronic logic
array is customized and implemented for MRI spectrometer [5][6].
The
implementation of 1.5 T MRI
spectrometer is as shown in figure1. The implemented design generates Multiple
RF output and captures multichannel coil / receiver channels for parallel
imaging algorithms. Multiple electrically automated RF coils [7] (each with an
RF chain) of MIMO [8], [9] are digitized with a very high precision digitize. An
Optimized implementation of a MIMO system with on chip quadrature signals processing
is done on the K-Space raw data to obtain the clinical images.Results
The SoC approach of MRI spectrometer is
developed and integrated with the Indian MRI system. Figure 4 shows one of the
images of a fruit scan performed. In this developed approach the data
processing relies heavily on the pulse sequence format in transmitter and FFT
transforms of the acquired data [10]. The
developed system interface helps in automatic calibration of MRI Scanners
related to Larmor frequency approach, generation of pulse amplitude modulation, design implementation for any
waveform with programmable width and arbitrary shape required for clinical
anatomical sequences to select multi slices of the human
anatomy, generate selective pulse sequences to distinguish fat or water,
generate waveforms for perfect image localisation, generation of three
axis gradient waveforms ,
pre-scan analysis, , Automatic RF power gain adjustments, flip angle
calibration, Transmitter and receiver
isolation, free induction decay analysis are some of the other features which
are mandatory for accurate spatial and temporal requirements.Conclusion
The implemented System on chip (SoC) MRI
spectrometer design is based on a 28 nanometer, single chip approach. An SoC,
comprising of multi-layered processor and programmable FPGA architectural layers.
This has helped to design and provide a highly customized, lower powered,
higher memory storage, smaller board size, with huge digital signal processing
slices. The design and development MRI spectrometer is numerically programmable
and up-gradable to various Tesla field scanners at a very minimal costs. Performance
evaluation of the system results in much faster and hassle free parallel
imaging algorithms in much lesser time duration. Acknowledgements
The author hereby acknowledges the support extended by MeitY,Government of India, for providing the financial support to carry out research and development of Indigenous Indian MRI project.References
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