Jeong Hee Yoon1
1Radiology, Seoul National University Hospital, Seoul, Korea, Republic of
Synopsis
MRI has been the ultimate diagnostic modality for
abdominal solid organs, however, relatively low accessibility of MRI due to its
cost and scan time is an issue for its wide application and limit its use.
Abbreviated MRI has gained a lot of attention to solve the aforementioned issue
and broaden the indications of MRI in the future. However, it is not yet
implemented in clinical practice due to some limitations. This presentation
aims to share the early experience on abbreviated MRI in practice and discuss
how abbreviated MRI may be moving forward to be successfully implemented in
clinical practice.
MRI has been the ultimate diagnostic modality for
abdominal solid organs- liver, pancreas, biliary tumors. However, the workflow
of MRI scan has been complex from the scheduling and image interpretation as
the recent techniques lead MRI sequences complex and long. So far, the role of
MRI has been an ultimate problem-solving tool in clinical practice. However,
now the paradigm of medical field is shifting to value-based practice rather
than leaning towards new, complex, on-the-edge medical techniques. In this
value-based era, the role of MRI should change, by embracing further
indications and ameliorating the complex workflow.
One of the attempts are abbreviated MRI in body
imaging. It refers to MRI scan without several sequences of full-protocol MRI.
The eliminated sequences could vary depending on purpose. This can be used for
routine diagnostic purpose, as well as for special screening/surveillance
purpose as well. There are reports which revealed comparable diagnostic
performances between the abbreviated MRI and full protocol MRI for
hepatocellular carcinomas (HCCs), liver metastases, pancreas cancers and
prostate cancers (1-6).
Although the results are promising, the
abbreviated protocol is not yet clinically implemented due to several reasons.
First, the optimal protocol is not established yet: For example, suggested
protocols for HCC surveillance vary from non-contrast MRI to extracellular
agent-enhanced MRI or hepatocyte-specific contrast media-enhanced MRI. Second,
the comparative efficacy is limitedly reported. Several studies compared full
protocol MRI and abbreviated MRI for diagnosis, but in case of cancer
surveillance, the comparison should be between the standard of care protocol
(e.g. ultrasound) and the abbreviated MRI. Further, retrospective study cannot
reflect the actual incidence of diseases and the predictive diagnostic yield of
abbreviated MRI protocol is not clearly addressed yet. Next, reporting
balancing sensitivity and specificity should be studied since MRI is an
expensive modality as a surveillance tool, and diagnostic modalities after
abbreviated MRI would be more expensive and invasive such as endoscopic
ultrasound or biopsy. Lastly, reducing sequence may not be sufficient to
maintain the diagnostic accuracy and reduce the scan time. Reducing sequence
should be performed with adopting new techniques to accelerate the total scan
time. The recommendation for protocol, cost, comparative efficacy comparing
with standard of care protocol and reporting are needed to be addressed to
implement it in clinical practice. In this talk, I will share my experience of
abbreviated MRI for cancer surveillance and discuss how to translate this
protocol to real clinical practice in the future in an inter-active manner.Acknowledgements
NRF-2020R1A2C2006031/National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT)
NRF-2021R1C1C1004569/Bio & Medical Technology Development Program of National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT)
References
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Jeon S, et al. Accelerated Pancreatobiliary MRI for Pancreatic Cancer
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