Translational Molecular CMR of Inflammatory & Cell Fate Processes
Gustav Strijkers1
1Academic Medical Center, Netherlands

Synopsis

Inflammation is a hallmark of multiple diseases and inflammatory factors can affect different systems in your body. Inflammatory cardiovascular diseases, including endocarditis and sarcoidosis, present a diagnostic challenge, and the inflammatory response after myocardial infarction stimulates adverse myocardial remodeling. Hence, there is a great need for the direct non-invasive visualization and quantification of myocardial inflammation to improve clinical diagnosis and decision making.In this educational presentation I will discuss the need for non-invasive imaging of inflammation and the pros and cons of several established and emerging MRI techniques for imaging of myocardial inflammation, including the use of iron-oxides and hyperpolarized substrates.

Inflammation is a hallmark of multiple diseases and the release of inflammatory factors can affect different systems in your body. Inflammatory cardiovascular diseases, including endocarditis, myocarditis, and sarcoidosis, present a diagnostic challenge, and the inflammatory response after myocardial infarction stimulates adverse myocardial remodeling. Hence, there is a great need for the direct non-invasive visualization and quantification of myocardial inflammation to improve clinical diagnosis and decision making.In this educational presentation I will discuss the need for non-invasive imaging of inflammation and the pros and cons of several established and emerging MRI techniques for imaging of myocardial inflammation, including the use of iron-oxide contrast agents and hyperpolarized substrates.

Acknowledgements

No acknowledgement found.

References

No reference found.
Proc. Intl. Soc. Mag. Reson. Med. 30 (2022)