In 2020 Wellcome launched an ambitious programme of work to understand how researchers feel about the cultures they work in. A consultation featuring <4,300 researchers was conducted, followed by 30 ‘townhall’-style events across the UK. Results indicated that 84% of researchers are proud to work in research but only 29% feel secure in pursuing this career. Women were also more likely to have experienced bullying or harassment (49%) than men (34%). The report provided evidence of widespread problems in research culture, and is being used by Wellcome as a touchpoint for solutions that will make careers in research more sustainable.