Synopsis

In this study we utilised a comprehensive, multinuclear MRI protocol which combines hyperpolarised 129Xe imaging methods sensitive to ventilation, lung microstructure (DW-MRI) and gas exchange (dissolved xenon spectroscopic imaging) alongside 1H DCE perfusion and UTE lung structural imaging to assess pathophysiological changes in patients who had been hospitalised with COVID-19 pneumonia, during the post-acute period.