The UK High Field Solid State NMR National Research Facility provides access to 20 T (850 MHz) and 23 T (1 GHz) spectrometers and probes capable of spinning samples at the Magic Angle at very high spinning frequencies (100 kHz). Under very fast MAS, the ¹H spin echo life time becomes considerably longer opening up the possibility to investigate ¹H-¹H proximities or to detect other atoms in vicinity to ¹H. For biological solids, the Facility has E-free (low-electric field, loop-gap loaded) coil MAS probes that allow efficient ¹H decoupling with minimal heating for the sample. The presentation showcases examples of enhanced resolution and sensitivity enabled by the 1 GHz NMR spectrometer and provides a basic description of some selected Solid-State NMR experiments performed at very fast Magic Angle spinning: for example, how sensitivity is enhanced for half-integer quadrupolar nuclei, and how 1H resolution is enhanced using Lee-Goldburg homonuclear decoupling.

Acknowledgements

The UK High-Field Solid-State NMR Facility used in this research was funded by EPSRC and BBSRC (EP/T015063/1)

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