This presentation will discuss the imaging findings seen in patients who have had treatment with immunotherapy. It will discuss the response criteria and the complications.

Acknowledgements

Dr Jazeari for images and data.

References

1.Cox, J.D., J. Stetz, and T.F. Pajak, Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European organization for research and treatment of cancer (EORTC). International Journal of Radiation Oncology*Biology*Physics, 1995. 31(5): p. 1341-1346. 2.Kammen, B.F., et al., Focal fatty infiltration of the liver: analysis of prevalence and CT findings in children and young adults. AJR Am J Roentgenol, 2001. 177(5): p. 1035-9. 3.Donadon, M., et al., Portal thrombosis and steatosis after preoperative chemotherapy with FOLFIRI-bevacizumab for colorectal liver metastases. World J Gastroenterol, 2006. 12(40): p. 6556-8. 4.Schouten van der Velden, A.P., et al., Hepatic veno-occlusive disease after neoadjuvant treatment of colorectal liver metastases with oxaliplatin: A lesson of the month. European Journal of Surgical Oncology (EJSO), 2008. 34(3): p. 353-355. 5.Erturk, S.M., et al., CT features of hepatic venoocclusive disease and hepatic graft-versus-host disease in patients after hematopoietic stem cell transplantation. AJR Am J Roentgenol, 2006. 186(6): p. 1497-501. 6.Khozouz, R.F., S.Z. Huq, and M.C. Perry, Radiation-induced liver disease. J Clin Oncol, 2008. 26(29): p. 4844-5. 7.Sugarbaker, P.H., Cytoreductive surgery and perioperative intraperitoneal chemotherapy: a new standard of care for appendiceal mucinous tumors with peritoneal dissemination. Clin Colon Rectal Surg, 2005. 18(3): p. 204-14. 8.Davila, M. and R.S. Bresalier, Gastrointestinal complications of oncologic therapy. Nat Clin Pract Gastroenterol Hepatol, 2008. 5(12): p. 682-96. 9.Khoury, N.J., et al., Abdominal complications of chemotherapy in pediatric malignancies: imaging findings. Clin Imaging, 2009. 33(4): p. 253-60. 10.Heinzerling, J.H. and S. Huerta, Bowel perforation from bevacizumab for the treatment of metastatic colon cancer: incidence, etiology, and management. Curr Surg, 2006. 63(5): p. 334-7. 11.Bruzzi, J.F., et al., PET/CT of esophageal cancer: its role in clinical management. Radiographics, 2007. 27(6): p. 1635-52. 12.Singh, A.K., et al., A prospective study of differences in duodenum compared to remaining small bowel motion between radiation treatments: implications for radiation dose escalation in carcinoma of the pancreas. Radiat Oncol, 2006. 1: p. 33. 13.Iyer, R. and A. Jhingran, Radiation injury: imaging findings in the chest, abdomen and pelvis after therapeutic radiation. Cancer Imaging, 2006. 6: p. S131-9. 14.Coia, L.R., R.J. Myerson, and J.E. Tepper, Late effects of radiation therapy on the gastrointestinal tract. Int J Radiat Oncol Biol Phys, 1995. 31(5): p. 1213-36.