Physiology of Intracranial Flow & Pressure
Marek Czosnyka 1
1University of Cambridge, Cambridge, United Kingdom

Synopsis

Cerebrospinal Fluid (CSF) flows continuously within all cavities of cerebrospinal space. Flow is slow, approximately 2000 times slower than Cerebral Blood Flow (CBF). Dynamic relationship between CBF and CSF circulation is complex, and involves basic physiological mechanism like cerebrovascular resistance, compartmental compliances, autoregulation of CBF, vascular impedance and critical closing pressure (CrCP). Proper functioning of CSF flow pathway is guaranteed by matching CSF production to absorption rate. This part of CSF steady circulation is easy to describe in a form of Davson's equation. Apart of circulation CSF displays some pulsatiles movments, which may be investigated using PCMRI.

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Proc. Intl. Soc. Mag. Reson. Med. 30 (2022)