This session will outline the key practical steps in translating a novel MRI method into the clinic. The challenges at each step will be discussed, with an emphasis on the important difference between clinical validation and demonstration of clinical utility.
My talk will be illustrated by examples of MRI methods which have been successful & unsuccessful at each stage of the translation process. In particular, we will consider whole-body MRI and quantitative cartilage MRI as exemplars of MRI methods which have been more or less successful in translation to the clinic.
Suggested pre-read:
O’Connor JPB, Aboagye EO, Adams JE, et al.: Imaging biomarker roadmap for cancer studies. Nature Reviews Clinical Oncology 2017; 14:169–186.