DENSE: A Technique in Translation
Xiaoying Cai1
1Siemens Healthineers, United States

Synopsis

Myocardial strain imaging is an important approach for quantifying cardiac function. Cine DENSE is a dedicated MR technique for strain imaging. By encoding tissue displacement into the phase of the imaging signal, cine DENSE allow rapid and comprehensive quantification of myocardial mechanics. This talk gives an overview of about cine DENSE imaging from data acquisition to reproducibility and its translation.

Target audience

Researchers and clinicians who are interested in myocardial strain imaging.

Outline

Cine DENSE is a technique developed for myocardial strain imaging. The method uses stimulated-echo imaging with displacement encoding. Post-processing extract information from the phase images to produce displacement fields and myocardial strain map. Previous studies have demonstrated highly reproducible measurement of both global and regional strains. Studies have also shown diagnostic and prognostic potentials of cine DENSE based strain quantification. In this talk, we will discuss the method on the following sections:
  1. Data acquisition and image processing
  2. Reproducibility
  3. Clinical potentials
  4. Translation
  5. Other considerations

Acknowledgements


References

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Mangion, Kenneth, et al. Radiology. 2018

Auger, Daniel A., et al. JMRI, 2017.

Bilchick, Kenneth C., et al. JACC: Cardiovascular Imaging 13.4 (2020): 924-936.

Proc. Intl. Soc. Mag. Reson. Med. 30 (2022)