Arterial spin labeling (ASL) MRI is a non-invasive technique to measure cerebral blood flow (CBF) and other hemodynamic parameters. In 2015, an ASL white paper was published on the clinical implementation of ASL, which largely harmonized the acquisition and processing of ASL MRI in basic science and clinical application. This has resulted in a broad acceptance of utilization of ASL MRI, as well as the adoption from MRI manufacturers. More recently, there are several ongoing efforts that aim to provide further recommendations on the use of multi-delay ASL to separately evaluate CBF and bolus arrival time (BAT), summary of the current status of velocity-selective (rather than spatially selective) ASL technique, updates on the recent advances in new ASL methodology, ASL MRI outside the brain, and review and recommendations on clinical applications of ASL. There is also an international initiative to standardize and enable open-source processing of ASL MRI data. This presentation will provide a summary of these latest progress.

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References

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