MR spectroscopic imaging enables mapping of spatial distribution of multiple low-concentration metabolites simultaneously. The detection of pathology-induced, altered brain metabolism has great potential in clinical research or diagnosis. High- and ultra-high-field MR systems opened new possibilities for MRSI acquisition with substantially improved spatial resolution, which historically hampered the clinical utility of MRSI. This lecture overviews fast encoding techniques, with which ultra-high-resolution 2D-/3D-MRSI has been achieved so far, as well as their first applications in basic research and clinical studies.