Magnetic resonance fingerprinting (MRF) is a novel quantitative MRI technique that enables the acquisition of multiparametric tissue property maps with high efficiency. In this talk, we will review principles of MRF and its advantages of generating multicontrast for brain imaging. We will review recent progress of using MRF for multicontrast normal brain atlases. We will also discuss applications of MRF on characterization of epileptic lesions and deep brain structures in patients with epilepsy. The talk will conclude with future direction on using the flexible framework of MRF to provide more contrasts for better depiction of pathologic processes.