Synopsis

COVID-19 has created havoc in communities around the world, ever since the start of the pandemic in December 2019. The causative agent, SARS-CoV-2 is a novel Coronavirus, that produces a diversity of manifestations ranging from asymptomatic infections to fatal infections characterized by viral pneumonia, ARDS, systemic inflammation and thromboembolism. The current presentation aims to summarize the pathogenesis and immunology of COVID-19 and its impact on vaccinations and the newly discovered viral variants.