Synopsis

This talk will cover MRI of brain development, including age-related neurodevelopment, normal variants, and diagnostic pitfalls, and key findings in neurogenetic disorders. We will review key mechanisms of pediatric brain development based on major embryologic steps including dorsal induction, ventral induction, formation of midline commissures, migration, and organization. We will cover MRI of fetal, perinatal, and postnatal development, including myelination, sulcation, basal ganglia, pituitary, and ventricular findings. Multiple imaging examples of congenital brain malformations will be presented, linking MRI findings to underlying derangements of neurodevelopmental processes.