Bedside MRI - Disruptions & Opportunities in Clinical Imaging Due to SARS-CoV-2
Justin Glavis-Bloom1, Brian Yep1, Lu-Aung Yosuke Masudathaya1, Jennifer Soun1, Edward Kuoy1, Lori Norrick1, Sara Stern-Nezer2, Wengui Yu3, John Fox4, and Daniel S. Chow1
1Radiological Sciences, University of California, Irvine, Irvine, CA, United States, 2Neurology & Neurological Surgery, University of California, Irvine, Irvine, CA, United States, 3Neurology, University of California, Irvine, Irvine, CA, United States, 4Emergency Medicine, University of California, Irvine, Irvine, CA, United States

Synopsis

Point-of-care, bedside MRI represents a promising new technology for imaging emergent and critical care patients. Whereas in the past, resources were needed to assemble teams that included critical care nurses, respiratory therapists, and transport teams to bring patients to and from radiology departments, there is a dramatic reduction in personnel for POC imaging. This feature was especially important during the COVID pandemic to improve availability of our respiratory therapists and nurses. More studies are needed in the future to ascertain its diagnostic sensitivity and specificity for neurologic findings.

Introduction

For patients with acute neurologic pathologies, early diagnosis and aggressive management may prevent aggravated or secondary injuries, thereby reducing mortality, morbidity, and healthcare costs1, 2. Diagnostic imaging with MRI is important in these patients when neurologic examinations are unattainable due to impaired consciousness3. Unfortunately, acquiring diagnostic brain MRIs for critical patients in intensive care units (ICUs) remains challenging, especially for patients who are often too medically unstable to transport. This feature was especially important during the COVID-19 pandemic given the surge of critically ill patients. One potential solution includes novel, bedside or point-of-care (POC) MRI, which has recently received Food and Drug Administration (FDA) approval (Hyperfine, Guilford, CT)4. This study shares our initial experience with a novel bedside MRI.

Methods

This is a retrospective observational series of patients who received a portable MRI at the University of California, Irvine from January 2021 through March 2021. We evaluated the number of cases from both Emergency Department (ED) and Intensive Care Unit (ICU) settings and descriptively report the number of diagnostic and nondiagnostic studies. For those with concurrent MRI with a fixed 1.5 tesla or 3.0 tesla MRI, we report whether new findings were observed. Lastly, we compared turnaround time (TAT), defined as time to order to study completion, of the POC MRI to our fixed MRIs.

Results

In total, POC MRI was conducted in 19 patients (7 ED and 12 ICU patients). Of the 19 MRIs, 17/19 (84%) were felt to be diagnostic. Of 8 patients who had a concurrent fixed MRI, 3/8 (38%) had a new finding. This included 2 patients who had initial nondiagnostic scans and 1 patient who had a 6 mm right thalamic infarct. Operationally, the TAT for acquiring a POC MRI was significantly faster compared to fixed MRI in both ED (2.9 hours versus 6.4 hours, p = 0.03) and ICU settings (9.2 hours versus 25.8 hours, p = 0.007). For ICU patients, this included 9 patients who were otherwise too unstable to bring to the MRI, including several COVID-19 patients.

Discussion

This initial pilot study demonstrates the initial the diagnostic utility of POC MRI, which was diagnostic for most of our patients. Whereas in the past, resources were needed to assemble teams that included critical care nurses, respiratory therapists, and transport teams to bring patients to and from radiology departments, there is a dramatic reduction in personnel for POC imaging. This feature was especially important during the COVID pandemic to improve availability of our respiratory therapists and nurses. In addition, we demonstrate operational improvements in POC MRI utilization.

Acknowledgements

No acknowledgement found.

References

1. Watts DD, Hanfling D, Waller MA, Gilmore C, Fakhry SM, Trask AL. An evaluation of the use of guidelines in prehospital management of brain injury. Prehosp Emerg Care. 2004 Jul-Sep 2004;8(3):254-61. doi:10.1016/j.prehos.2004.02.001

2. Fakhry SM, Trask AL, Waller MA, Watts DD, Force INT. Management of brain-injured patients by an evidence-based medicine protocol improves outcomes and decreases hospital charges. J Trauma. Mar 2004;56(3):492-9; discussion 499-500. doi:10.1097/01.ta.0000115650.07193.66

3. Lee B, Newberg A. Neuroimaging in traumatic brain imaging. NeuroRx. Apr 2005;2(2):372-83. doi:10.1602/neurorx.2.2.372

4. K192002, Lucy Point-Of-Care Magnetic Resonance Imaging Device (2020).

Proc. Intl. Soc. Mag. Reson. Med. 29 (2021)