Synopsis

Dynamic contrast enhanced MRI (DCE-MRI) is a completely established method for tumor assessment. Technically it is a series of T1w images acquired before and after contrast agent administration. DCE-MRI visualizes tumor vascularisation and neoangiogenesis. Trade-off between high spatial and high temporal resolution is crucial. Evaluation is made visually or in a semi-quantitative manner, for clinical trials also via a full quantitative model. Rapid wash in and early wash out are the most suspicious findings for malignancy. Possible alternatives are Dynamic Susceptibility Contrast (DSC), Arterial Spin Labeling (ASL) and Dynamic Contrast Enhanced Computer Tomography DCE-CT.