This presentation will overview the technologies and clinical application of MRI-guided robotic prostate biopsy. Robotic devices have been developed and clinically tested in recent years to address technical challenges in MRI-guided prostate biopsy, such as the limited access to the patient in the bore, and suboptimal needle placement accuracy. I will discuss the technologies for MR-guided robotic biopsy from several key aspects, including system architecture, MRI compatibility, kinematics design, software, imaging sequences, and evaluation of needle placement accuracy. Additionally, I will review some of the published studies that have demonstrated the clinical feasibility of MRI-guided robotic prostate biopsy.