MRI of the breast is a very important technique in breast imaging. The combination of multiple techniques, such as dynamic contrast-enhanced (DCE) MRI, T2-weighted and diffusion weighted imaging (DWI) within the same examination is called multi-parametric MRI (mpMRI). mpMRI protocol interrogates different characteristics of breast tumor and with the combined information an improved diagnosis and characterization of breast tumors is facilitated. Advanced functional techniques are currently being investigated for its clinical value and potential integration in a multiparametric MRI protocols. A case-based presentation will be offered to let the audience familiarize with the most used multiparametric breast MRI protocols.